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Last update: Pátková Vlasta (08.06.2018)
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Last update: Pátková Vlasta (08.06.2018)
Students will know:
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Last update: Lankaš Filip doc. Ing. Ph.D. (15.11.2022)
B: N. Haspel, F. Jagodzinsky, K. Molloy (eds.), Algorithms and Methods in Structural Bioinformatics, Springer 2022 B: S. Neidle and M. Sanderson, Principles of Nucleic Acid Structure, 2nd ed., Academic Press 2021 R: Z. Gaspari (ed.), Structural Bioinformatics Methods and Protocols, Springer 2020 |
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Last update: Pátková Vlasta (08.06.2018)
Online course materials |
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Last update: Kubová Petra Ing. (17.06.2018)
1. Protein-protein and protein-nucleic acid interactions 2. Gibbs free energy calculation methods for biomolecular interactions 3. Docking algorithms for protein-protein and protein-DNA interactions 4. Software, servers and web interfaces for predicting biomolecular interactions 5. Protein Structure Initiative and computational proteomics 6. Interactome and protein interaction networks 7. Prediction of induced fit 8. Protein design and peptide docking using ab initio methods 9. Sequence dependent structural properties of DNA and their functional role 10. RNA secondary structure prediction 11. Modeling of 3D RNA structure 12. Integrative structural bioinformatics – combining experimental data and computational methods 13. – 14. Case studies |
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Last update: Pátková Vlasta (08.06.2018)
Mathematics, physical chemistry, algorithms and programming, and biochemistry or molecular biology at the level of basic university courses |
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Last update: Pátková Vlasta (08.06.2018)
Oral exam |