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Last update: Fusek Martin prof. Ing. CSc. (08.02.2018)
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Last update: Krausová Martina doc. Ing. Ph.D. (11.01.2018)
Students will be able to: gain knowledge of the overall work flow of laboratories, quality control of analytical methods as well as other diagnostic laboratory methods used in medical practice. |
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Last update: Kubová Petra Ing. (19.12.2017)
R:Schneiderka P. a kol., Stanovení analytů v klinické biochemii,1.část, Praha, Karolinum,1999, 80-7184-761-5 R:Schneiderka P. a kol., Kapitoly z klinické biochemie,Karolinum, 2004, 80-246-0678-X A:Zima T. a kol.: Laboratorní diagnostika, třetí doplněné a přepracované vydání, Praha, Galén, 2013, 978-80-7262-372-3(Galén), 978-80-246-1423-6 (Karolinum) A:Racek, J. a kol.: Klinická biochemie. Druhé, přepracované vydání Galén + Karolinum, Praha, 2006, 80-7262-324-9 A:Štern, P.a kol.: Obecná a klinická biochemie. Praha, Karolinum, 2011, 978-80-246-1979-8 A: Mačák J., Mačáková J. a Dvořáčková J.: Patologie. 2., doplněné vydání. Grada Publishing 2012, 978-80-247-3530-6 |
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Last update: Kubová Petra Ing. (19.12.2017)
none |
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Last update: Lipovová Petra doc. Ing. Ph.D. (09.08.2023)
Předmět je zakončen písemnou a ústní zkouškou |
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Last update: Krausová Martina doc. Ing. Ph.D. (11.01.2018)
1. Introduction Clinical biochemistry / definition, history, basic tasks / Overview of lectured themes / Basic materials analysed in a clinical laboratory / Quality biochemical analysis / Safety 2. Methods in Clinical Biochemistry I Separation Methods / Analytical methods / Molecular genetic analysis / Molecular diagnostics 3. Methods in Clinical Biochemistry II Immunochemical methods / Summarization of the testing - Basic investigated parameters / Specific tests 4. Metabolism of amino acids Overview of amino acid / Amino acid metabolism / Metabolic disorders and their detection 5. Proteins and clinical biochemistry Main types and functions of protein / Protein metabolism - synthesis and degradation / Examination protein / Main clinically significant plasma proteins / Proteins recovered in the urine 6. Enzymes - function and disorders The role of enzymes in the body / Determination of enzymatic activity / Main enzymes in clinical biochemistry and their determination 7. Carbohydrate metabolism and its disorders Carbohydrates and their metabolism / Physiological functions of carbohydrates / Diabetes and its examination / Other disorders of carbohydrate metabolism 8. Lipids and their metabolism Structure and physiological functions / Digestion and transport / Apolipoproteins / Enzymes of lipid transport / Atherosclerosis / Biochemical screening 9. Liver functions and related biochemical screening Liver - description and metabolism / Liver diseases / Analytical procedures for the diagnosis of liver diseases 10. Renal functions and related biochemical screening Kidney - description and function / Main biomarkers for the diagnosis of renal functions / Analytical Methods 11. Hormones and their analysis Classification and functions of basic hormone / Clinical applications 12. Tumor markers Cancer diseases / Classification of tumor markers / Use of tumor markers 13. Electrolytes Basic terms / Main monitored ions / Sodium and Potassium 14. Acid-base balance Processes affecting pH / Role of carbon dioxide / pH control / ABB parameters |
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Last update: Krausová Martina doc. Ing. Ph.D. (11.01.2018)
Biochemistry I |
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Last update: Fusek Martin prof. Ing. CSc. (25.01.2018)
Succesfully pass two written tests and the oral examination. |
Teaching methods | ||||
Activity | Credits | Hours | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na zkoušku a její absolvování | 2 | 56 | ||
3 / 3 | 84 / 84 |