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The course introduces basic and structurally derived groups of natural substances, their properties, reactions, occurrence and function in nature, including living organisms. It also explains basic concepts related to the structure of molecules, their stereochemistry and chirality, including the relationship between the structure of a substance and its biological activity. The course also deals with the biosynthesis of important types of natural substances and enzyme and biomimetic reactions. Emphasis is placed on the medical significance of the described natural substances.
Last update: Jurášek Michal (05.05.2025)
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R: McMurry J.: Organic chemistry, 8th Ed., Brooks/Cole, Cengage Learning, 2012, 9780840054449 Last update: Kubová Petra (19.12.2017)
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1. Secondary metabolism 2. Acetate pathway 3. Shikimate pathway 4. Mevalonate and methylerythritol pathways 5. Alkaloids 6. Proteins and peptides 7. Carbohydrates Last update: Jurášek Michal (05.05.2025)
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Lecture notes Last update: Jurášek Michal (05.05.2025)
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Students will be able to: Classify natural substances into individual structural classes. Describe the structure, properties and reactions of individual classes of natural substances and their biogenesis. Describe the relationships between structure and reactivity. Illustrate the reaction mechanisms of basic types of reactions. Characterize the medicinal importance of natural substances. Last update: Jurášek Michal (05.05.2025)
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Organic Chemistry I or Organic Chemistry A or Bioorganic Chemistry of Natural Substances, Biochemistry I and II, Microbiology Last update: Jurášek Michal (05.05.2025)
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