Drug design - M402020
Title: Návrh léčiv
Guaranteed by: Department of Analytical Chemistry (402)
Faculty: Faculty of Chemical Engineering
Actual: from 2023 to 2023
Semester: both
Points: 3
E-Credits: 3
Examination process:
Hours per week, examination: 2/0, Ex [HT]
Capacity: winter:unlimited / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: course can be enrolled in outside the study plan
enabled for web enrollment
you can enroll for the course in winter and in summer semester
Guarantor: Dolenský Bohumil doc. Ing. Ph.D.
Interchangeability : N402056
Examination dates   
Annotation -
The search for new pharmaceuticals using knowledge of biological objectives is a complex matter. This course is focused on the chemical nature of this problem.
Last update: Pátková Vlasta (05.01.2018)
Aim of the course -

Students will be able to apply a variety of techniques to address the problems associated with the emergence of new medicines.

Last update: Pátková Vlasta (05.01.2018)
Literature -

R: http://www.vscht.cz/kot/cz/studijni-materialy.html

R: http://www.alga.cz/users/tichym/AMB/12_drugdiscovery.ppt

R: http://www.cc.nih.gov/training/training/principles/slides/DrugDevProgram08-09oneslide.pdf

A: http://mediaserver.aapspharmaceutica.com/meetings/DDS/Integration%20of%20In%20Silico%20Models%20in%20Drug%20Design.pdf

A: http://pharm.swu.ac.th/web_npec/content/JOURNAL/LectureAutoDock.pdf

A: http://www.cc.nih.gov/training/training/principles/slides/DrugDevProgram08-09oneslide.pdf

Last update: Pátková Vlasta (05.01.2018)
Learning resources -


Last update: Pátková Vlasta (05.01.2018)
Syllabus -

1.The identification of biological target.

2.The targeting of drugs on proteins.

3.The targeting of drugs on DNA.

4.Other biological targets.

5.Drug Design: computational methods.

6.Molecular modeling, Docking.

7.Design of anti-cancer agents by function and target biological structure.


9.Design of anti-virals.

10.Antivirals I.

11.To provide drugs for CNS.

12.To provide drugs for CVS.

13.Natural substances such as structural elements for modern pharmaceuticals I.

14.Natural substances such as structural elements for modern pharmaceuticals II.

Last update: Pátková Vlasta (05.01.2018)
Registration requirements -


Last update: Pátková Vlasta (05.01.2018)
Course completion requirements - Czech

Zkouška probíhá formou písemné i ústní zkoušky.

Last update: Vosmanská Magda (21.02.2018)
Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 0.3 8
Příprava na zkoušku a její absolvování 1.7 48
3 / 3 84 / 84