SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Isolation and Identification of Natural Compounds - N342022
Title: Izolace a identifikace přírodních látek
Guaranteed by: Department of Chemistry of Natural Compounds (342)
Actual: from 2017
Semester: summer
Points: summer s.:4
E-Credits: summer s.:4
Examination process: summer s.:
Hours per week, examination: summer s.:2/1 C+Ex [hours/week]
Capacity: 48 / 48 (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
For type:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Prokudina Elena Ing. Ph.D.
Kofroňová Edita Mgr. Ph.D.
Examination dates   Schedule   
Annotation -
Last update: TAJ342 (01.10.2013)
The course is aimed at understanding of isolation and separation techniques used for separations of complex mixtures of compounds obtained from natural materials or prepared in a laboratory. Emphasized are alternative methods and selection of a suitable method according to the properties of a target organic compound. After product isolation it is necessary to identify and characterize a given compound. For that reason, attention is paid to suitable physico-chemical methods.
Aim of the course -
Last update: TAJ342 (01.10.2013)

Students will be able to:

Optimize basic processes for isolation of organic compounds from a mixture

Identify organic compounds and interpret the results at a basic level

Assess product purity from spectral data

Decide between alternative isolation and separation methods

Literature -
Last update: TAJ342 (01.10.2013)

R: Fogler H.S., Elements of Reaction Engineering, Prentice, Hall, New Jersey,2000,0130473944

Learning resources -
Last update: TAJ342 (01.10.2013)

Lecture notes

Syllabus -
Last update: TAJ342 (01.10.2013)

1. Introduction, problem formulation, process characterization, definition of starting conditions

2. Removing solid particles: filtration, microfiltration, ultrafiltration, treatment of suspension before filtration

3. Centrifugation (common centrifuges), comparison of filtration and centrifugation

4. Extraction (batch, counter-flow), modification of distribution coefficient, pH, ion pairs formation

5. Adsorption (batch, continuous)

6. Sorbents, overview and applications, mobile phase selection

7. Chromatography: theoretical description of a phenomenon, instrumentation, analytical and preparative arrangement

8. Chromatography: yield, purity

9. Electro migration methods

10. Economical aspects of alternative methods, solvent regeneration, operation safety

11. Physico-chemical methods of identification of organic compounds

12. UV, VIS, and IR spectrometry, applications

13. Nuclear magnetic resonance, principle, applications

14. Mass spectrometry, principle, applications

Registration requirements -
Last update: TAJ342 (01.10.2013)

Organic chemistry I

Mathematics I

Course completion requirements - Czech
Last update: MORAVCOJ (21.11.2012)

Napsání zápočtového testu

Ústní zkouška

Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 1,5 42
Účast na seminářích 0,5 14
4 / 4 112 / 112
Coursework assessment
Form Significance
Regular attendance 20
Continuous assessment of study performance and course -credit tests 30
Oral examination 50

 
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