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Last update: Masák Jan prof. Ing. CSc. (11.05.2022)
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Last update: Masák Jan prof. Ing. CSc. (12.05.2022)
Students will know the advanced biotechnological processes used in the industrial production of various types of pharmaceuticals; they will understand the nature of biosynthesis and its control in different types of producers; they be able to compile a theoretical design of a technological process for the production of a compound; they gain a comprehensive overview of the production of pharmaceuticals using biotechnological processes.
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Last update: Masák Jan prof. Ing. CSc. (12.05.2022)
R: Murray Moo-Young (Ed.) Comprehensive Biotechnology 3rd edition, Pergamon 2019.
A: D. J. A. Crommelin et.al. Pharmaceutical Biotechnology 4th edition, Springer 2013.
A: B. H. Lee. Advanced Fermentation and Cell Technology, Wiley Blackwell 2022. |
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Last update: Masák Jan prof. Ing. CSc. (11.05.2022)
https://onlinelibrary-wiley-com.ezproxy.vscht.cz/doi/book/10.1002/14356007 |
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Last update: Masák Jan prof. Ing. CSc. (12.05.2022)
1. Introduction - the participation of biotechnological processes in the pharmaceutical industry
2. Development of biological agents for biotechnology - microorganisms, tissue cultures, higher eukaryotes
3. Modification and regulation of metabolism to achieve high drug overproduction
4. Characteristics of unit operations of downstream and upstream processes in biotechnology
5. Biotechnological production of polyketides
6. Biotechnological production of other antibiotics
7. Biotechnological production of anticancer drugs
8. Biotechnological production of pharmaceutically important alkaloids and other toxins
9. Biotechnological production of vitamins
10. Biotechnological production of polysaccharides
11. Therapeutic enzymes
12. Industrial biotransformations for the production of precursors and products in pharmacy
13. Vaccines
14. Other biopharmaceuticals
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Last update: Masák Jan prof. Ing. CSc. (11.05.2022)
Successful completion of the oral exam. |