SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Bioactive Natural Compounds - S342009A
Title: Bioactive Natural Compounds
Guaranteed by: Department of Chemistry of Natural Compounds (342)
Actual: from 2019
Semester: summer
Points: summer s.:5
E-Credits: summer s.:5
Examination process: summer s.:
Hours per week, examination: summer s.:3/0 Ex [hours/week]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: English
Teaching methods: full-time
Level:  
Is provided by: AM342001
For type:  
Guarantor: Lapčík Oldřich prof. Dr. RNDr.
Mikšátková Petra PharmDr. Ph.D.
Examination dates   Schedule   
Literature
Last update: Lapčík Oldřich prof. Dr. RNDr. (19.11.2012)

Jean Bruneton: Pharmacognosy. Lavoisier Publishing Inc., Paris, 1999, reprint 2001.

ISBN: 1-898298-63-7

2. Paul M. Dewick: Medicinal Natural Products � A Biosynthetic Approach. John Wiley

& Sons Ltd., Chichester, England. 2002. ISBN 0471 49641 3

3. Joanne Barnes, Linda A. Anderson, J. David Philipson: Herbal Medicines.

Pharmaceutical Press, London, UK 2007. ISBN 978 0 85369 623 0

Syllabus - Czech
Last update: Šmídová Ludmila (20.01.2012)

History of the subject, Basic terms. Pharmacognosy and chemosystematics.

Cellular and molecular targets of biological activity.

Polysacharides: Fibers, gums, mucillages and pectins - plants: Acacia sp., Astragalus gummifer, Ceratonia siliqua, Psilium sp., Agar agar

Specifically active proteins: Enzymes, lectins, protein sweeteners - plants: Carica papaya., Canavalia ensiformis, Ricinus communis, Abrus precatorius, Thaumatococcus sp.

Alkaloids I: Generalities, taxonomical occurance, protoalkaloids.

Alkaloids II. Selected types of alkaloids and their biological activities - plants: Atropa belladona, Erythroxylon cocca, Nicotiana sp., Areca catechu, Conium maculatum,Papaver somniferum, Cataranthus roseus, Strychnos nux-vomica, Physostigma venenosum

Alkaloids III. Ergot alkaloids, pseudoalkaloids, purine alkaloids. - plants: Claviceps purpurea, Aconitum sp. Veratrum sp., Coffea arabica, Camelia sinensis, Theobroma cacao, Ilex paraguayensis

Glycosylation, Specific examples of bioactive glycosides: Cardiac glycosides, saponins, glucosinolates, cyanogenic glycosides. - plants: Digitalis sp, Drimia maritima, Glycyrrhiza glabra, Aesculus hippocastanum, Hedera helix, Brassica sp., Manihot esculenta.

Phenolics I: Generalities. Phenolic acids and their esters, coumarins. - plants: Myroxylon balsamum, Rosmarinus officinalis, Salix sp., Meliotus officinalis, Heracleum sp.

Phenolics II: Flavonoids and lignans. Phytoestrogens. - plants: -Silybum marianum, Fagopyrum esculentum, Glycine max., Trifolium sp, Linum usitatissimum

Phenolics III. Tannins. Quinones and floroglucinols. - plants: -Quercus sp., Juglans regia, Lawsonia inermis, Cassia sp., Rhamnus frangula, Humulus lupulus, Cannabis sp.

Terpenoids I: Monoterpenes and essential oils. Toxic diterpenes. - plants: -Lavandula sp., Mentha sp., Thymus sp, Carum carvi, Citrus aurantium, Taxus sp., Croton sp., Daphne mezerum

Terpenoids II: Triterpenoids, steroids and carotenoids. Vitamin A and retinoids. - plants: -Betula sp., Cucurbita sp., Capsicum annuum, Crocus sp.,

Excursion (Botany Garden)

 
VŠCHT Praha