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Chemical and pharmaceutical industry extends the use of biotechnological processes for obtaining new compounds or for reducing costs and environmental impact of the production of current compounds. Introductory lectures will provide detailed information about the current range of implementation of biotechnological processes in these industries. Attention is also given to explain the procedures for development of industrial strains achieving the high production of required compounds. The various types of processes are then discussed using examples of production of particular substances applied in the chemical and pharmaceutical industries. Special attention is paid to biotransformation processes. In the seminar, students work out individual theme the output of which is the design of a biotechnological process for the production of a selected substance.
Last update: TAJ319 (11.12.2013)
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Students will be able to: select appropriate procedures for the preparation of industrial biological agents (microorganisms, enzymes, plant or animal tissue culture); generally suggest biotechnological process for the production a substance; evaluate the process, health and economic risks of a particular biotechnology; apply extensive knowledge in the design of biotechnological processes in the chemical and biotechnology industries Last update: Masák Jan (30.08.2013)
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R:Moo-Young, M:Comprehensive Biotechnology (2nd ed.), Elsevier, Amsterdam, 2011,9780080885049 A:Rehm,H.-J.,Reed G.: Biotechnology, 12 Vols., 2nd Ed, Wiley, Weinheim, 2008,9783527620821 A:Flickinger, M.C.: Encyclopedia of Bioprocess Technology, Wiley, 2008,9780471250586 A:Ho, R.J.Y: Biotechnology and Biopharmaceuticals, Wiley, 2003,0471206903 Last update: TAJ319 (30.08.2013)
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1. Introduction - the status of biotechnology in the chemical and pharmaceutical industry 2. Characteristics of biotechnological processes 3. The development of industrial strains - physiological adaptation, gene modification, transformation of higher organisms 4. Biotechnological production of primary and secondary metabolites - unit operations, process management, economic balance 5. Biotechnological production of biopharmaceuticals - characteristics of the processes 6. Biotransformation - basic characteristics of the processes 7. Biotransformation - examples 8. Antibiotics - characteristics, production organisms, technological processes 9. Antibiotics - the current state of world production, research and development 10. Cancerostatics - characteristics, production organisms, technological processes 11. Alkaloids - characteristics, production organisms, technological processes 12. Vitamins - characteristics, production organisms, technological processes 13. Enzymes - characteristics, production organisms, technological processes 14. Polysaccharides - characteristics, production organisms, technological processes Last update: Masák Jan (30.08.2013)
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http://eso.vscht.cz/ Last update: Masák Jan (30.08.2013)
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Biochemistry, Microbiology, Bioengineering Last update: Masák Jan (30.08.2013)
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| Teaching methods | ||||
| Activity | Credits | Hours | ||
| Konzultace s vyučujícími | 0.3 | 7 | ||
| Obhajoba individuálního projektu | 0.3 | 7 | ||
| Účast na přednáškách | 1 | 28 | ||
| Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi | 0.5 | 14 | ||
| Práce na individuálním projektu | 0.9 | 26 | ||
| Příprava na zkoušku a její absolvování | 1 | 28 | ||
| Účast na seminářích | 1 | 28 | ||
| 5 / 5 | 138 / 140 | |||
| Coursework assessment | |
| Form | Significance |
| Regular attendance | 30 |
| Defense of an individual project | 20 |
| Report from individual projects | 10 |
| Oral examination | 40 |