Subjects

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Biochemistry I - S320001

Title:	Biochemistry I
Guaranteed by:	Department of Biochemistry and Microbiology (320)
Faculty:	Faculty of Food and Biochemical Technology
Actual:	from 2019 to 2020
Semester:	winter
Points:	winter s.:5
E-Credits:	winter s.:5
Examination process:	winter s.:
Hours per week, examination:	winter s.:3/1, C+Ex [HT]
Capacity:	unlimited / unlimited (unknown)
Min. number of students:	unlimited
State of the course:	taught
Language:	English
Teaching methods:	full-time
Level:

Guarantor:	Hynek Radovan prof. Dr. Ing. Valentová Olga prof. RNDr. CSc.
Interchangeability :	N320002

Examination dates Schedule

Annotation -

The subject is focused on understanding of basic principles of biochemistry; it means structure and function of different biological molecules as well as metabolism.

Last update: Hynek Radovan (20.10.2015)

Course completion requirements -

Successful completion of seminars (including required tests) and both written and oral part of exam.

Last update: Hynek Radovan (25.01.2018)

Literature -

R: Lehninger Principles of Biochemistry, Fourth Edition; David L. Nelson; Michael M. Cox; Published by W. H. Freeman (2004) ISBN 10: 0716743396 ISBN 13: 9780716743392

Last update: Hynek Radovan (20.10.2015)

Syllabus -

1. Living systems, their composition and organization

2. Amino acids (properties, determination and reaction) and peptides

3. Proteins (relation between structure and function)

4. Enzymes: Structure, nomenclature, classification into classes

5. Reaction kinetics of enzymatic reactions, regulation of enzyme activity

6. Chemistry of nucleotides and nucleic acids; replication

7. Transcription, translation, and posttranslational modifications

8. Chemistry of lipids. Biomembranes and membrane transport

9. The principles of metabolism and energy conversion; bioenergetics

10. Aerobic and anaerobic respiration, Light phase of photosynthesis

11. Citrate and glyoxylate cycle

12. Chemistry of carbohydrates. Metabolism of Carbohydrates I.

13. Metabolism of Carbohydrates II. Metabolism of lipids.

14. Metabolism of nitrogenous substances

Last update: Hynek Radovan (24.01.2018)

Learning resources -

Extended syllabus (available upon request).

Last update: Hynek Radovan (20.10.2015)

Learning outcomes -

Students will be able to:

Understand basic principles of biochemistry; it means structure and function of different biological molecules including correlation between their structure and function, principals of enzyme catalysis and division of enzymes into basic classes, functions of biological membranes and membrane transport, basic concept of metabolism and energy conversion, major metabolic pathways including photosynthesis and nitrogen compounds metabolism.

Last update: Hynek Radovan (20.10.2015)

Registration requirements -

None.

Last update: Hynek Radovan (20.10.2015)

Teaching methods
	Activity	Credits	Hours
	Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi	0.5	14
	Příprava na zkoušku a její absolvování	5	140
	Účast na seminářích	0.5	14
		6 / 5	168 / 140

Coursework assessment
Form	Significance
Regular attendance	5
Examination test	40
Continuous assessment of study performance and course -credit tests	15
Oral examination	40