|
|
|
||
|
Cílem předmětu je seznámit posluchače s problematikou bioinformatiky, jejími cíli a postupy.
Last update: SMIDOVAL (18.05.2011)
|
|
||
|
J. Xiong, Essential Bioinformatics, Cambridge University Press 2006, ISBN 0521600820 J.-M. Claverie, C. Notredame, Bioinformatics For Dummies, For Dummies 2006, ISBN 0470089857 M. Zvelebil, J. Baum, Understanding Bioinformatics, Garland Science 2007, ISBN 0815340249 Last update: SMIDOVAL (18.05.2011)
|
|
||
|
K zápočtu a ke zkoušce bude požadováno:
1. Test v polovině semestru
2. Písemná zkouška Last update: SMIDOVAL (18.05.2011)
|
|
||
|
1) Background basics I - Structure of DNA and RNA. The central dogma. Gene structure and control. 2) Background basics II - Evolution. Protein structure and its implication for bioinformatics. Dealing with databases. 3) Sequence alignment I - Pairwise sequence alignment. Similarity database searching. 4) Sequence alignment II - Multiple sequence alignment. Profiles and Hidden Markov Models. 5) Genome characteristics - Gene Detection and Genome Annotation. Promoter and regulatory element prediction. 6) Evolutionary processes - Recovering evolutionary history. Building phylogenetic trees. 7) Structural bioinformatics I - Protein structure basics. Nucleic acid structure basics. 8) Structural bioinformatics II - Prediction of protein structure 9) Structural bioinformatics III - Prediction of nucleic acids structure (RNA) 10) Proteome and gene expression analysis 11) High throughput screening experiments and their analysis 12) Data mining in bioinformatics 13) Biomedical text mining Last update: SMIDOVAL (18.05.2011)
|