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Chemical and Pharmaceutical Process Engineering course is aimed at providing the understanding of the unit operations employed in the pharmaceutical industry, in the chemical part of API synthesis, as well as in the dosage form manufacturing. Operations or their aspects that are beyond the scope of general chemical engineering courses constitute the essential part of this course. The understanding of the unit operations and process principles is supported by substantial amount of insight into properties of particulate solids, considering their key role in contemporary solid dosage forms design and manufacturing, and also by introductory course into the process control and safety. Last update: Zámostný Petr (06.08.2018)
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Students will be able to: Analyze and optimize basic processes in chemical and pharmaceutical industry Create protocols and operating sheets compliant with the industrial standards Design suitable approach for scaling up the process from laboratory to production scale Last update: Zámostný Petr (06.08.2018)
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R:Rhodes M.,Introduction to Particle Technology,Wiley,New York,2008,0471984833 R:Hickey A.J.,Pharmaceutical Process Engineering,M.Dekker,2001,0824702980 A:Levin M.,Pharmaceutical process scale up,M.Dekker,2002,0824706250 A:Klefenz H.,Industrial Pharmaceutical Biotechnology,Wiley,N.Y.,2002,3527299955 A:Fogler H.S.,Elements of Reaction Engineering,Prentice,Hall,New Jersey,2000,0130473944 Last update: Zámostný Petr (06.08.2018)
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1. Characteristics and characterization of particles and particulate systems 2. Particle size reduction and classification 3. Introduction to mechanics of particulate solids 4. Particle agglomeration processes, high-shear, and fluidized-bed granulation 5. Compaction processes 6. Extrusion and postprocessing of agglomerated products 7. Tablet compression 8. Mixing and segregation in particulate systems 9. Pharmaceutical processes scale up, general scale up considerations 10. Fluid flow and transport in pharma applications 11. Processes involving particulate solid interaction with liquids 12. Applied reaction kinetics 13. Reaction kinetics of biotechnological processes 14. Introduction to process control, safety considerations in chemical and pharmaceutical processes
Last update: Zámostný Petr (07.08.2018)
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Public available older version http://tresen.vscht.cz/kot/english/tag/pharmaceutical-engineering/ New materials are available on UCT E-learning system Last update: Zámostný Petr (07.08.2018)
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Mathematics I, Unit Operations of Chemical Engineering I Last update: Zámostný Petr (07.08.2018)
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