Industrial synthesis of fine chemicals - AP111013
Title: Industrial synthesis of fine chemicals
Guaranteed by: Department of Organic Technology (111)
Faculty: Faculty of Chemical Technology
Actual: from 2022
Semester: summer
Points: summer s.:0
E-Credits: summer s.:0
Examination process: summer s.:
Hours per week, examination: summer s.:2/0, other [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Level:  
Note: course is intended for doctoral students only
can be fulfilled in the future
Guarantor: Vyskočilová Eliška doc. Ing. Ph.D.
Examination dates   
Annotation -
The lectures deal with the special chemical products designed for the final consumer. The fine chemicals or chemical specialties are pharmaceuticals, pesticides, fragrances, surfactants and colorants, and other products. The important factors of industrial syntheses of chosen compounds will be described together with basic structures and mechanisms of action. Ecological aspects of the production will be also included.
Last update: Vyskočilová Eliška (11.07.2022)
Aim of the course -

Students will be able to:

describe the chemistry application in different products

understand the basic principles of effects of fine chemicals and the basics of syntheses

describe the basics of industrial production and the use of the fine chemical categories

define the difference between the industrial production of fine and basic chemical

Last update: Vyskočilová Eliška (11.07.2022)
Course completion requirements -

Activity on the lectures and sucesfully passed oral exam.

Last update: Vyskočilová Eliška (11.07.2022)
Literature -

Z: Wiley-VCH, Ullmann's Fine Chemicals, Wiley-VCH; 1st edition (January 7, 2014), ISBN 978-3527334773

D: Stephen O. Duke, Per Kudsk, Keith Solomon, Pesticide Dose: Effects on the Environment and Target and Non-Target Organisms, ACS Symposium series, 2017, ISBN13: 9780841232112, DOI: 10.1021/bk-2017-1249

D: F. Muller, Agrochemicals: Composition, Production, Toxicology, Applications, Wiley-VCH 2000 ISBN-13 ‏ : ‎ 978-3527298525

D: D. Cairns, Essentials of Pharmaceutical Chemistry 4th Edition, Pharmaceutical Press; 4th edition (January 1, 2012), ISBN 978-0853699798

D: D. Myers, Surfactant Science and Technology, Wiley; 4th edition (June 23, 2020). ISBN 978-1119465850

D: Hans Zweifel, Plastics Additives Handbook, Hanser Publications; 6th edition (June 4, 2009), ISBN 978-1569904305

Last update: Vyskočilová Eliška (11.07.2022)
Syllabus -

1. Introduction to the subject, definition of fine chemicals, and differences between basic and special products.

2. Types of fine chemicals, division of products according to useful properties, borderline cases.

3. Biologically active substances - basic procedures in industrial production, work safety.

4. Pharmaceuticals - production of basic types, selected processes.

5. Pesticides - differences in the production of drugs and agrochemicals. Toxicological tests.

6. Pesticides - mechanism of action and effect on non-target organisms.

7. Insecticides, rodenticides, and fungicides - basic structural types and their production.

8. Herbicides - basic structural types. Ecological aspects of the use of agrochemicals.

9. Fragrances and flavors - production and use of basic types, the relationship between the structure and properties of BAL.

10. Additives for plastics, production, possible biological effects (phthalates, retarders, etc.)

11. Surfactants - properties, production, and use of anionic surfactants.

12. Nonionic and cationic surfactants, ecological aspects of production, and use of surfactants.

13. Basic types of dyes and pigments, differences in production and use.

14. Functional colorants, ecological aspects of production, and use of dyes.

Last update: Vyskočilová Eliška (11.07.2022)
Learning resources -

https://en.wikipedia.org/wiki/Fine_chemical

Last update: Vyskočilová Eliška (11.07.2022)