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Last update: Cibulková Jana Ing. (06.07.2022)
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Last update: Cibulková Jana Ing. (06.07.2022)
Students will be able to: describe the most important macromolecular systems for targeted drug delivery and controlled drug release, they will learn the methods of their synthesis and eventual practical applications. |
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Last update: Cibulková Jana Ing. (06.07.2022)
R:Glen S. Kwon, ed.: Polymeric Drug Delivery Systems (Drugs and the Pharmaceutical Sciences), Taylor and Francis Group, Boca Raton 2005. R:Ijeoma F. Uchegbu, Andreas G. Schatzlein, eds.: Polymers in Drug Delivery, Taylor and Francis Group, Boca Raton 2006. R:T. Prnka, K. Šperlink: Bionanotechnologie, nanobiotechnologie, nanomedicína, Repronis, Ostrava, 2006, ISBN 80-7329-134-7. http://www.nanotechnologie.cz/view.php?cisloclanku=2007080009 A:Hest, J. C. M. van. Biosynthetic-Synthetic Polymer Conjugates. Polym. Rev. 2007, 47, 63-92. A:Magnusson, J. P.; Saeed, A. O.; Fernández-Trillo, F.; Alexander, C. Synthetic Polymers for Biopharmaceutical Delivery. Polym. Chem. 2011, 2, 48. A:Zhou, Y.; Kopeček, J. Biological Rationale for the Design of Polymeric Anti-Cancer Nanomedicines. J. Drug Target. 2013, 21, 1-26. A:Liu, S.; Maheshwari, R.; Kiick, K. L. Polymer-Based Therapeutics. Macromolecules 2009, 42, 3-13. |
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Last update: Cibulková Jana Ing. (06.07.2022)
1. History of polymer drug 2. Polymer drug carriers with various structure 3. Active and passive targeting of polymer drugs 4. Polymer cancerostatics 5. Selection and binding of targeting ligands 6. Solid phase peptide synthesis 7. Polymers in gene therapy 8. Covalent versus non-covalent methods of binding proteins to polymers 9. Polymer drugs in clinical trials and clinical practice |
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Last update: Cibulková Jana Ing. (06.07.2022)
prezentation of scientific paper, oral exam |