SubjectsSubjects(version: 956)
Course, academic year 2021/2022

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Analysis of Solid Pharmaceuticals - B108004
Title: Analýza pevných léčiv
Guaranteed by: Department of Solid State Chemistry (108)
Faculty: Faculty of Chemical Technology
Actual: from 2021
Semester: winter
Points: winter s.:3
E-Credits: winter s.:3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, Ex [HT]
Capacity: unlimited / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Additional information: http://výuka probíhá pouze v zimním semestru
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Čejka Jan Ing. Ph.D.
Interchangeability : N108021
Annotation -
Lectures are focused on selected analytical methods used in pharmaceutical industry. Solid state techniques, polymorphism, solvatomorphism, mixtures, etc. are accented.
Last update: Kubová Petra (03.01.2018)
Aim of the course -

The students will be able to:

be oriented in basic crystallography and in selected analytical techniques;

choose optimal method to analyse API's or related impurities, considering the nature od the compounds either crystalline obr amorphous, polymorph transformations, co-crystals, mixtures, etc.;

analyse relative and absolute configuration.

Last update: Kubová Petra (03.01.2018)
Literature -

R:Kraus I.,Struktura a vlastnosti krystalů,Academia,Praha,1993,802000372X

Last update: Kubová Petra (03.01.2018)
Learning resources -

Electronical version of study materials

Last update: Kubová Petra (03.01.2018)
Syllabus -

1. Macroscopic assembly And symmetry od solid state compounds

2. Microscopic organization And symmetry in solid state

3. Single crystal X-ray analysis

4. X-ray powder analysis

5. Quality parameters of X-ray data, software available

6. Databases CSD, PDB, PDF

7. X-ray fluorescence analysis

8. Solid state NMR

9. IR and Raman spectroscopy

10. Thermal methods - TG, DTA, DSC, HSM, DVS


single crystal X-ray analysis

powder and fluorescence X-ray analysis

IR and Raman spectroscopy

Thermal methods

Last update: Kubová Petra (03.01.2018)
Entry requirements - Czech

Pro zápis tohoto předmětu je nutno mít minimálně zapsán předmět N108022

Last update: Kubová Petra (03.01.2018)
Registration requirements -

No pre-requisites

Last update: Kubová Petra (03.01.2018)
Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 1 28
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