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Last update: Kubová Petra Ing. (03.01.2018)
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Last update: Kratochvíl Bohumil prof. RNDr. DSc. (09.01.2018)
Students will be able to: understand the internal structure and arrangement of crystal and amorphous phases of solid pharmaceutical ingredients (API) knowledgeable in polymorphism of anhydrates, hydrates, salts, cocrystals predict possible degradation processes and products of solid API‘s |
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Last update: Kratochvíl Bohumil prof. RNDr. DSc. (09.01.2018)
R:Hilfiker R.(Ed.), Polymorphism in the Pharmaceutical Industry, Wiley-VCH Verlag, Weinheim, Germany, 2006, 9783527311460 |
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Last update: Kratochvíl Bohumil prof. RNDr. DSc. (13.02.2018)
https://uchpel.vscht.cz/studium/studijni_materialy |
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Last update: Kratochvíl Bohumil prof. RNDr. DSc. (09.01.2018)
1. Introduction to pharmaceutical solids 2. Crystal and amorphous phases 3. Molecular solids 4. Crystallization 5. Solubility and dissolution 6. Phenomenon of polymorphism 7. Examples of polymorphic systems 7. Solid forms of API’s (anhydrates, hydrates, salts, cocrystals) 8. Amorphous pharmaceutical phases 9. Size a shape of particles 10. Microstructure of dosage forms 11. Degradation processes in solids, stability tests 12. Photodegradation 13. Hygroscopicity 14. Patents |
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Last update: Kratochvíl Bohumil prof. RNDr. DSc. (13.02.2018)
Organic chemistry I, II
Fundamentals of Pharmacology
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