SubjectsSubjects(version: 902)
Course, academic year 2021/2022
  
Isolation and Identification of Natural Compounds - B342005
Title: Izolace a identifikace přírodních látek
Guaranteed by: Department of Chemistry of Natural Compounds (342)
Actual: from 2021
Semester: summer
Points: summer s.:4
E-Credits: summer s.:4
Examination process: summer s.:
Hours per week, examination: summer s.:2/1 [hours/week]
Capacity: unlimited / unlimited (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
For type:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Prokudina Elena Ing. Ph.D.
Interchangeability : N342022
This subject contains the following additional online materials
Annotation -
Last update: Fialová Jana (18.12.2017)
The course is aimed at understanding of isolation and separation techniques used for separations of complex mixtures of compounds obtained from natural materials or prepared in a laboratory. Emphasized are alternative methods and selection of a suitable method according to the properties of a target organic compound. After product isolation it is necessary to identify and characterize a given compound. For that reason, attention is paid to suitable physico-chemical methods.
Aim of the course -
Last update: MORAVCOJ (01.02.2018)

Students will be able:

to understand physical-chemical principles of isolation and identification of organic compounds

to optimize basic processes for isolation of organic compounds from a mixture

to identify organic compounds and interpret the results at a basic level

to assess product purity from spectral data

to decide between alternative isolation and separation methods

Literature -
Last update: Fialová Jana (18.12.2017)

R: Fogler H.S., Elements of Reaction Engineering, Prentice, Hall, New Jersey,2000,0130473944

Learning resources -
Last update: Fialová Jana (18.12.2017)

Lecture notes

Syllabus -
Last update: MORAVCOJ (01.02.2018)

1. Introduction, problem formulation, up and down stream processes, economical aspects, operation safety

2. Features of organic and inorganic compounds suitable for separation, economical aspects, operation safety

3. Overview of down stream processes, fundamental characteristics, alternative methods

4. Removing solid particles: filtration, microfiltration, ultrafiltration, treatment of suspension before filtration, centrifugation

5. Extraction (batch), optimization of distribution coefficient, pH, ion pairs formation

6. Adsorption: solid-liquid batch, adsorption isotherms, mass balance

7. Sorbents, overview and applications, mobile phase selection

8. Chromatography: theoretical description of a phenomenon, instrumentation, analytical and preparative arrangement

9. Chromatography: elution liquid chromatography, Gauss equation, yield and purity of fractions

10. Electro migration methods, analytical and preparative, gas chromatography, stationery phases, instrumentation

11. Destillation, crystallization, drying, precipitation

12. UV, VIS, X-ray, and IR spectrometry, applications

13. Nuclear magnetic resonance, principle, applications

14. Mass spectrometry, principle, applications

Registration requirements -
Last update: Fialová Jana (18.12.2017)

Organic chemistry I

Mathematics I

Course completion requirements - Czech
Last update: MORAVCOJ (27.02.2018)

Napsání zápočtového testu nad 50 %

Ústní zkouška

 
VŠCHT Praha