Last update: Jirků Vladimír prof. RNDr. DrSc. (12.06.2018)
With an emphasis on the applied aspects of the subject area, the course is designed to integrate selected topics of cell and molecular biology. In this context, the presented overview of advanced factography meets the demands of expected future engagement of a post-graduate student in the area of biotechnology in general, and in its biopharmaceutical, food and environmental sectors, in particular. Syllabus: The course (as an advanced) is structured as follows: 1. Module: regulatory mechanisms used by single cell to sense its extracellular environment. 2. Module: the biology of multicellular consortia, including polymicrobial infections and the biology of microbiomes. 3. Module: cellular sensitivity, resistence; host-pathogen interactions. This course is aimed at post-graduate students, who have already passed courses prescribed for the undergraduates in the branch of biotechnology
Students will be able to differentiate and recognize potentially applicable cell function in in the background of the cell type diversity and actual demands of the current Applied Biology / Biotech R&D.
Recent scientific papers (among others) will be recommended during the course; students are expected to select own reading sources.
R: Glenn F., Molecular Biology and Pathogenesis, Academic Press, 2014, 978-1-908230-30-0
R: Glick B., Molecular Biotechnology, ASM Press, 2003, 978-1-55581-224-9
R: Datar R., Concepts in Applied Molecular Biology,BioTechniques Press,2003, 1-881299-30-9
R: Romani M., Aquatic Biofilms,Caister Academic Press, 2016, 978-1-910190-17-3
A: Fuentes M., Proteomics, Academic Přes, 2014, 978-1-908230-46-1
A: Lear G., Biofilm in Bioremediation,Caister Academic Press, 2016,978-1-910190-29-6
A: Kaufmann S.,The Innate Immune Response to Infection, ASM Press, 2004, 978-1-55581-291-1
A: Siber G., Pneumococcal Vaccines, ASM Press, 2008, 978-1-55581-408-3
A: Cossart P., Cellular Microbiology, ASM Press, 2004, 978-1-55581-302-4
A: Sanchez S., Antibiotics,Caister Academic Press, 2015,978-1-908230-54-6
A: Coste A., Antifungals, Caister Academic Press, 2015,978-1-910190-01-2
A: Fleming D., Biological Safety:.. ASM Press, 2006, 1-55581-339-9
Aids to study
Lectures, partly combined with the intention to create an interactive lecture segment.
The lecture topics illustrate advanced applicable knowledge regarding techologically significant cell processes, functions and properties as well as potential utility of different cell types (incl. artificial cell comparatments) in different fields of biotechnology. This course is designed to help students summarize selected knowledge of different biological disciplines and understand the main R&D streams in the area of advanced applied biology.
Requirements to pass the course
Oral presentation evaluation (students are required to have their topic /s approved)