SubjectsSubjects(version: 944)
Course, academic year 2021/2022
Biophysical Chemistry - D320016
Title: Biofyzikální chemie
Guaranteed by: Department of Biochemistry and Microbiology (320)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2016
Semester: winter
Points: winter s.:0
E-Credits: winter s.:0
Examination process: winter s.:
Hours per week, examination: winter s.:0/0, other [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
For type:  
Note: course is intended for doctoral students only
can be fulfilled in the future
Guarantor: Holík Purkrtová Zita Ing. Ph.D.
Marková Michaela Ing. Ph.D.
Annotation -
Last update: Holík Purkrtová Zita Ing. Ph.D. (19.10.2015)
The lectures are focused on description of physical-chemical aspects of biological systems and use of physical-chemical terms to describe and solve the problems in biological systems. Students will have an overview of the most important concepts and methodology of modern biophysical chemistry as well as structural methods for description of biomacromolecules.
Aim of the course -
Last update: Holík Purkrtová Zita Ing. Ph.D. (19.10.2015)

Students will be able to:

Describe basic biochemical processes by mathematical methods used in physical chemistry.

Apply the principles of physical chemistry in interpretation and solving problems occuring in biological systems. The problems solution includes numerical analysis of chosen physical chemistry parameters.

Independently propose a method and design a protocol for experimental determination of chosen physical chemistry parameters in biological systems and analyse obtained data.

Literature -
Last update: Holík Purkrtová Zita Ing. Ph.D. (19.10.2015)

R: Atkins P.,de Paula J., Physical Chemistry for the Life Sciences, Oxford University Press, 2011, 978-0-19-956428-6

R: Bergethon P.R., The Physical Basis of Biochemistry, Springer-Verlag New York Inc., 1998, 0-387-98262-0

A: Nelson D.L., Cox M.M., Lehninger Principles of Biochemistry, W.H.Freeman, 2008, 978-0716771081

Learning resources -
Last update: Holík Purkrtová Zita Ing. Ph.D. (19.10.2015)

Syllabus -
Last update: Holík Purkrtová Zita Ing. Ph.D. (19.10.2015)

1. Position of biophysical chemistry in the system of natural science

2. Bioenergetics I

3. Bioenergetics II (non-equilibrium thermodynamics)

4. The importance of noncovalent interactions for biological systems

5. The general characteristics of protein structure

6. Methods of kinetics measurement of biological processes

7. Pharmacokinetics

8. Structure and function of biological membranes

9. Biological processes associated with membranes: biochemistry of vision, electron transport chain and photosynthesis

10. Electrochemical processes in biological systems

11. The use of spectrophotometry in biochemical laboratory

12. The use of radiochemistry for the study of biological processes

13. Methods for the study of protein structure I: NMR and X-ray crystallography

14. Methods for the study of protein structure II: circular dichroism and fluorescence spectroscopy

Registration requirements -
Last update: Holík Purkrtová Zita Ing. Ph.D. (19.10.2015)


Physical chemistry