SubjectsSubjects(version: 949)
Course, academic year 2023/2024
Physical Organic Chemistry - M110016
Title: Fyzikální organická chemie
Guaranteed by: Department of Organic Chemistry (110)
Faculty: Faculty of Chemical Technology
Actual: from 2023
Semester: summer
Points: summer s.:5
E-Credits: summer s.:5
Examination process: summer s.:
Hours per week, examination: summer s.:2/2, C+Ex [HT]
Capacity: 13 / 13 (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
For type: Master's (post-Bachelor)
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Krupička Martin Ing. Ph.D.
Interchangeability : N110007
This subject contains the following additional online materials
Annotation -
Last update: Kubová Petra Ing. (10.01.2018)
The aim of this course is to acquire knowledge about mechanism of organic reactions based on the analysis of structural and electronic factors present in reactants and products.
Aim of the course -
Last update: Kubová Petra Ing. (10.01.2018)

Students will be able to :

understand basic concept of physical organic chemistry

use of various methods of study of reaction mechanisms

understand reaction mechanisms of common chemical reactions

elucidate the relations between structure and reactivity of organic compounds

Literature -
Last update: Kubová Petra Ing. (10.01.2018)

R: Böhm S. : Fyzikální organická chemie, CD verze učebního textu

A: Eric V. Anslyn, Dennis A. Dougherty : Modern Physical Organic Chemistry. 1891389319

Learning resources -
Last update: Kubová Petra Ing. (10.01.2018)

Lectures on CD

Syllabus -
Last update: Kubová Petra Ing. (10.01.2018)

1. Structure and mechanism

2. Kinetic studies

3. Linear Gibbs energy relations

4. Acids and bases

5. The reaction medium

6. MO theory

7. Aliphatic nucleophilic substitution

8. Elimination reactions

9. Addition to C=C double bonds

10.Aromatic electrophilic substitution

11.Addition to C=O group and related reactions

12.The hydrolysis of carboxylic esters

13.Aromatic nucleophilic substitution

14.Molecular rearrangements

15.Aliphatic radical substitution

16.Pericyclic reactions

Registration requirements -
Last update: Kundrát Ondřej Ing. Ph.D. (10.01.2018)


Course completion requirements -
Last update: Kundrát Ondřej Ing. Ph.D. (16.02.2018)

The examination has written and oral part.

Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 2 56
Účast na seminářích 1 28
5 / 5 140 / 140