SubjectsSubjects(version: 882)
Course, academic year 2020/2021
Chemical kinetics and transport phenomena in pharmaceutical applications - M111017
Title: Chemická kinetika a přenosové jevy ve farmaceutických aplikacích
Guaranteed by: Department of Organic Technology (111)
Actual: from 2020
Semester: winter
Points: winter s.:5
E-Credits: winter s.:5
Examination process: winter s.:
Hours per week, examination: winter s.:2/2 C+Ex [hours/week]
Capacity: unlimited / unlimited (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
For type: Master's (post-Bachelor)
Guarantor: Čapek Pavel doc. Ing. CSc.
This subject contains the following additional online materials
Annotation -
Last update: Čapek Pavel doc. Ing. CSc. (29.07.2020)
The course thematically expands the course "Engineering of Chemical and Pharmaceutical Processes”. The course is focused on chemical kinetics, mass balance in ideal types of chemical reactors and processing of experimental kinetic data from homogeneous and selected heterogeneous reaction systems. Furthermore, attention is paid to transfer phenomena in fluids at phase interfaces. In addition to mass transfer, heat transfer and the interaction of these phenomena are also discussed to a limited extent. Porous media and capillary phenomena are also included in the scope of the subject.
Aim of the course -
Last update: Čapek Pavel doc. Ing. CSc. (29.07.2020)

Students will be able to:

1. Formulate kinetic equations according to the assumed mechanism of chemical reactions and process kinetic data from ideal types of chemical reactors;

2. Orientation in the issue of physical and chemical processes associated with the transport of mass and heat and with pharmaceutical applications;

3. Qualitatively estimate the flow of mass and heat through phase interfaces and membranes.

Literature -
Last update: Čapek Pavel doc. Ing. CSc. (29.07.2020)

R: H.S.Fogler, Elements of Chemical Reaction Engineering, Prentice Hall, New Jersey, 2006, 0130473944

R: R. B. Bird, W. E. Stewart, E. N. Lightfoot: Transport Phenomena, 2nd edition, John Wiley & Sons, New York (2007), 0470115394.

R: J. Dressman, J. Kraemer: Pharmaceutical Dissolution Testing, Taylor & Francis Group, New York (2005), 824754679.

A: R. C. Reid, J. M. Prausnitz, B. E. Poling: The Properties of Gases & Liquids, 4th edition, McGraw-Hill, Boston (1987), 0470115394.

Requirements to the exam -
Last update: Čapek Pavel doc. Ing. CSc. (29.07.2020)

two/three written tests and oral examination

Syllabus -
Last update: Čapek Pavel doc. Ing. CSc. (29.07.2020)

1. Definitions of the rate of chemical reaction and relationships between the reaction rates and stoichiometric equations.

2. Kinetic equations, the influence of concentrations of substances and temperature on the rate of irreversible reactions.

3. Influence of concentrations of substances and temperature on the rate of reversible reactions. The role of chemical equilibrium.

4. Elementary reactions. Reaction systems, definition of selectivity and yield. Side, consecutive and autocatalytic reactions.

5. Kinetic equations for catalytic reactions.

6. Determination of kinetic equations and experiments in laboratory types of reactors.

7. Phase interfaces: Porous substances and capillary phenomena.

8. Mechanisms of mass and heat transport.

9. Transport of mass and heat through the phase interface.

10. Mass transport through a semipermeable barrier (membrane).

11. Determination of mass and heat transfer coefficients.

12. Mutual influence of mass and heat transport and chemical reactions.

13. Percolation phenomena and two-phase flow of immiscible fluids through porous substances.

14. Case studies.

Registration requirements -
Last update: Čapek Pavel doc. Ing. CSc. (29.07.2020)

Mathematics I

Physical Chemistry I

Unit Operations of Chemical Engineering I

Engineering of Chemical and Pharmaceutical Processes

Course completion requirements - Czech
Last update: Patera Jan Ing. Ph.D. (21.02.2018)

Student musí úspěšně napsat tři zápočtové testy, které všechny musí být hodnoceny alespoň 17 body ze 40 možných. Následně musí uspět u ústní zkoušky.

Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 2 56
Účast na seminářích 1 28
5 / 5 140 / 140