SubjectsSubjects(version: 947)
Course, academic year 2021/2022
  
Selected Chapters from Chemistry and Technology of Polymers II - M112013
Title: Vybrané kapitoly z chemie a technologie polymerů II
Guaranteed by: Department of Polymers (112)
Faculty: Faculty of Chemical Technology
Actual: from 2020
Semester: winter
Points: winter s.:3
E-Credits: winter s.:3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Level:  
For type: Master's (post-Bachelor)
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Merna Jan prof. Ing. Ph.D.
Interchangeability : N112041
This subject contains the following additional online materials
Annotation -
Last update: Hrdlička Zdeněk doc. Ing. Ph.D. (18.10.2022)
The lectures are given only in even years and is NOT a continuation of Selected chapters I. Subject is composed of three modules, 8 hours each: 1. Living/controlled polymerizations (Prof. J. Merna) Definitions, mechanisms of controlled polymerizations, strategies of macromolecular architectures synthesis, physico-chemical properties and application of advanced polymer systems. 2. Additive manufacturing (Dr. A. Sokolohorskyj) Basic processes of 3D printing. Design and model building for 3D printing. Polymeric materials for 3D printing. Conventional and less conventional technologies of 3D printing. 3. Polymers for drug delivery and release (Dr. R. Laga) Overview of polymer systems for targeted drug transport and controlled drug release. Principals of controlled drug release, systems for controlled drug release in organism (matrix systems, membrane systems, systems for transdermal delivery, polymer systems with activated drug release, nanoparticles, liposomes, soluble polymer carriers, vectors for gene therapy). Controlled drug delivery, systems with passive and active targeting.
Aim of the course -
Last update: Hrdlička Zdeněk doc. Ing. Ph.D. (18.10.2022)

Students will be able to:

  • suggest a suitable method for controlled synthesis of basic polymer architectures;
  • suggest a suitable method of 3D printing of polymeric materials;
  • understand the principles of controlled drug release, students will get an overview about basic polymer systems for drug delivery and release.

Literature -
Last update: Hladíková Jana (04.01.2018)

R:Poole Jr. Ch.P., Owens F.J.: Introduction to Nanotechnology, John Wiley & Sons, Inc., 2003; ISBN 0-471-07935-9

A:Gauglitz G., Vo-Dinh T.: Handbook of Spectroscopy, Part II, Methods 1: Optical Microscopy, Wiley-VCH Verlag GmbH & Co. KGaA, published on-line, 2003; ISBN 3527297820

R:Müller, A. H. E., Matyjaszewski, K.: Controlled and living polymerizations : methods and materials, Weinheim : Wiley-VCH, 2009; ISBN 978-3-527-32492-7

A:Hadjichristidis N. et al. Complex macromolecular architectures : synthesis, characterization, and self-assembly, Singapore : Wiley, 2011. ISBN 978-0-470-82513-6

A:Krzysztof Matyjaszewski, Controlled/Living Radical Polymerization: Progress in ATRP, NMP, and RAFT, Volume 768, 2000, ACS Symposium Series, American Chemical Society Washington DC, 2000; ISBN 0-8412-3707-7

R:Glen S. Kwon Ed.: Polymeric Drug Delivery Systems. Taylor&Francis, Bocca Raton, London, New York, Singapore 2005.; ISBN 9780824725327(selected chapters)

A: Ram I. Mahato Ed.: Biomaterials for Delivery and Targeting of Proteins and Nucleic Acids.CRC Press 2005. ISBN 9780849323348,(selected chapters)

Learning resources -
Last update: Hrdlička Zdeněk doc. Ing. Ph.D. (18.10.2022)

Electronic version of lecture presentations available from teachers for registered students.

Syllabus -
Last update: Hrdlička Zdeněk doc. Ing. Ph.D. (18.10.2022)

Living/controlled polymerizations (Prof. J. Merna)

1.Definition, polymer architectures overview, synthetic strategies, click-chemistry

2.Controlled ionic polymerizations

3. Controlled radical polymerizations (ATRP, NMP, RAFT, DT, SET LRP)

4. Controlled coordination polymerizations, self-assembly vs. structure-morphology, characterization methods

Additive manufacturing (Dr. A. Sokolohorskyj)

5. Additive manufacturing. History and development. Basic processes, design and model building for 3D printing.

6.+ 7. Technology and polymeric materials for 3D printing – photopolymerization, powder bed fusion, hot melt extrusion deposition.

8. Droplet-based and other unconventional methods of 3D printing. 3D printing of metals, glass abd ceramics. Assessment of additive manufacturing in practice.

Polymers for drug delivery and release (Dr. R. Laga)

9. Overview of polymer systems for controlled drug release, principals of controlled drug release

10. Targeted drug delivery, matrix systems for drug release. Nondegradable and biodegradable hydrophobic polymer systems

11. Hadrogel based systems. Membrane polymer systems for controlled drug release, systems for transdermal drug delivery .

12. Polymer systems with activated drug release. Soluble drug carriers.

13./14. Examination test from all three modules.

Entry requirements - Czech
Last update: Hrdlička Zdeněk doc. Ing. Ph.D. (18.10.2022)

Makromolekulární chemie.

Registration requirements -
Last update: Hrdlička Zdeněk doc. Ing. Ph.D. (18.10.2022)

Macromolecular chemistry

Course completion requirements - Czech
Last update: Hrdlička Zdeněk doc. Ing. Ph.D. (18.10.2022)

Zisk nejméně 50 % bodů z písemného zkouškového testu zahrnujícího otázky ze všech tří modulů.

 
VŠCHT Praha