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The aim is to obtain an overview and basic understanding of blood and blood elements and their properties. The skill to apply this knowledge in immunochemistry and medicine. There is information on the structure and function of blood and blood cells, immune system, innate and acquired immunity and its regulation, the use of immunochemistry in analytic chemistry and medicine, on hemostasis and thrombosis and hematological and immunological disorders.
Last update: Hladíková Jana (13.12.2017)
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Students will acquire: basic knowledge in hematology and immunology and immunochemical methods in analytical chemistry and medicine Last update: Hladíková Jana (13.12.2017)
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completed continuous, written and oral exams Last update: Hochel Igor (25.01.2018)
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R:Bartůňková J., Hořejší V., Základy imunologie, TRITON, 2011, 978-80-7387-280-9, EAN: 9788073872809 R:Daussant J., Desvaux F.X., Introduction to Immunochemical Techniques for Medical Diagnosis, Food Quality Control and Environmental Testing, Praha, 2007, 978-80-7080-641-8 R:Penka M., Tesařová E. a kolektiv, Hematologie a transfuzní lékařství, 1. Hematologie, 2011, 978-80-247-3459-0 A:Krejsek J., Kopecký O., Klinická imunologie, Nucleus HK, 2004, 80-86225-50-X A:Klener P., Vnitřní lékařství, 2011 (4. vydání), EAN: 9788072627059, 978-80-7262-705-9, 80-7262-705-8 Last update: Hladíková Jana (13.12.2017)
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1) Hematology, blood, plasma, blood cells and blood elements, hematopoetic cells, cell proliferation and differentiation, blood cells forming organs 2) Deficit and surplass of blood cells, anemia, myeloproliferative and lymphoproliferative disorders and hematologic malignancies 3) Hemostasis and thrombosis, blood coagulation, platelets, fibrinolytic system 4) Laboratory diagnostic methods in blood coagulation and thrombosis, hemocompatibility 5) Introduction to immunology and immunochemistry, cells of the immune system 6) Innate and acquired immune system, the immune response 7) Complement 8) Major histocompatibility system, lymphocytes and their functions 9) Antibodies - immunoglobulin class structure and function, antigens - structure and function, interaction antibody - antigen, antibody - affinity, specificity, cross-reactions 10) Immunity disorders 11) Immunization - polyclonal antisera production, isolation of antibodies, their purification and characterization, monoclonal antibodies - production and properties 12) Imunochemical methods - general approach; enzyme immunoassays 13) Application of immunochemical methods in medicine, hematology, cytology, histochemistry 14) Application of antibodies and immunological techniques in medicine Last update: Hochel Igor (25.01.2018)
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none Last update: Hladíková Jana (13.12.2017)
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Biochemistry, Enzymology Last update: Hochel Igor (25.01.2018)
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Teaching methods | ||||
Activity | Credits | Hours | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi | 1 | 28 | ||
Příprava na zkoušku a její absolvování | 1 | 28 | ||
3 / 3 | 84 / 84 |
Coursework assessment | |
Form | Significance |
Regular attendance | 30 |
Examination test | 10 |
Continuous assessment of study performance and course -credit tests | 10 |
Oral examination | 50 |