SubjectsSubjects(version: 955)
Course, academic year 2019/2020
Pathobiochemistry II - M320007
Title: Pathobiochemie II
Guaranteed by: Department of Biochemistry and Microbiology (320)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2019 to 2020
Semester: summer
Points: summer s.:3
E-Credits: summer s.:3
Examination process: summer s.:
Hours per week, examination: summer s.:2/0, Ex [HT]
Capacity: unlimited / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Šebesta Ivan MUDr. CSc.
Jirsa Milan prof. MUDr. Mgr. CSc.
Interchangeability : N320031
Examination dates   Schedule   
Annotation -
The goal of the subject is to acquire basic pathobiochemistry processes in the human body. The course emphasizes a comprehensive explanation of the mechanisms of disease development at the level of tissues, cells and molecular biology,too. Students are also acquainted with effective indication and interpretation of basic biochemical tests. ) The latest research findings and treatment of diseases with high frequency (lifestyle diseases) are also presented.
Last update: Hladíková Jana (13.12.2017)
Aim of the course -

Students will able to:

Students will learn pathobiochemistry of common diseases, they will get deep knowledge on civilisation diseases and they will understand basic assays in clinical biochemistry diagnostics.

Last update: Hochel Igor (01.02.2018)
Literature -

R:Masopust J., Patobiochemie buňky. ČSKB, 2.LF UK, 2003, 80-239-1011-0

R:Masopust J., PrůšaR., Patobiochemie metabolických drah, 2.LFUK, 1999, 80-238-4589-6

R:Kalousová M. a kol., Patobiochemie ve schématech, Grada Publishing, 2006, 80-247-1522-8

R:Racek J. a kol., Klinická biochemie.2.vydání, Praha, Galén, Karolinum, 2006, 80-7262-324-9

R:Štern P. a kol., Obecná a klinická biochemie, Karolinum, Praha 2011, 978-80-246-1979-8

R:Karlson P., Gerok W., Gross W., Pathobiochemie, Academia, Praha 1987 (nemá ISBN)

A:Zima T. ed. Laboratorní diagnostika, třetí, doplněné a přepracované vydání, Praha, Galén, 2013, 978-80-7262-372-3(Galén), 978-80-246-1423-6 (Karolinum)

Last update: Hochel Igor (01.02.2018)
Learning resources -

Last update: Hladíková Jana (13.12.2017)
Syllabus -

1.Urine and pathobiochemistry of renal functions

2.Acid-base balance

3.Pathobiochemistry of connective tissue and bones

4.Pathobiochemistry of nervous and muscle tissue

5.Principles of hormonal regulation and its disorders,axis of hypothalamus and hypophysis

6.Adrenal cortex hormones and sex hormones

7.Thyroid and parathyroid hormones

8.Pathobiochemistry of malabsorption

9.Endocrine and exocrine pancreas

10.Biochemistry of malignant tumor

11.Biochemistry of inflammation

12.Vitamins, hypo- and hypervitaminosis

13.Xenobiochemistry and biotransformation of drugs


Last update: Hladíková Jana (13.12.2017)
Registration requirements -


Last update: Hochel Igor (31.01.2018)
Course completion requirements -

Oral exams

Last update: Hochel Igor (31.01.2018)
Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 1 28
3 / 3 84 / 84
Coursework assessment
Form Significance
Regular attendance 10
Oral examination 90