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In the course, students will learn about the different groups of pathogens, their most important representatives and the diseases caused by them. They will also learn the principles of prevention (vaccination) and treatment (antibiotics, antifungals, antiparasitics and antivirals) of infectious diseases. Attention will also be paid to the development of resistance. In selected cases, the basic principles and mechanisms of the life cycle of microorganisms will be described. Students will also be introduced to clinical microbiology laboratory methods.
Last update: Častorálová Markéta (15.09.2023)
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A: Hurych, J.; et al. Lékařská mikrobiologie - repetitorium, 3.rd ed.; Triton: Praha, 2021. 978-80-7553-976-2 R: M. Votava a kol., Lékařská mikrobiologie speciální, Neptun, Brno, 2003, 80-902896-6-5 R: M. Votava, Lékařská mikrobiologie obecná, Neptun, Brno, 2005, 80-86850-00-5 R: M. Votava a kol., Lékařská mikrobiologie vyšetřovací metody, Neptun, Brno, 2010, 978-80-86850-04-8 Last update: Častorálová Markéta (15.09.2023)
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1. Introduction. Historical development and importance of medical microbiology. Natural microbiota. 2. Antibiotics, their division, mechanisms of action, emergence of resistance. Basics of immunity. Vaccination, vaccines. Mandatory and recommended vaccinations, vaccination calendar. 3. Virulence factors of bacteria - mechanism, description and distribution, toxins. 4. Classification of bacteria and their diagnosis, culture media, procedure for obtaining samples and their processing. 5. Clinically important G+ cocci (Micrococcus, Staphylococcus, Streptococcus, Enterococcus) and rods (Listeria, Bacillus, Clostridium). 6. G-facultatively anaerobic rods (family Enterobacteriaceae, Vibrionaceae, Pasteurellaceae). 7. Other clinically important G- bacteria (Pseudomonas, Bordetella, Brucella, Francisella, Legionella, Helicobacter, Campylobacter, Neisseria). 8. Completion of clinically important G+ bacteria (Nocardia, Cutibacterium) and non-traditional G+ and G- bacteria (Mycobacterium, Mycoplasma, Chlamydia, Rickettsia, Bartonella). Spirochetes (Borrelia, Treponema). 9. Clinically important micromycetes (yeasts, fungi), mycotoxins, antifungals. 10. Clinically important parasites, antiparasitics. 11. Viruses - definition, history, classification of viruses. Diagnosis, vaccination, antivirals. Prions. 12. Representatives of DNA viruses (Papillomaviridae, Polyomaviridae, Adenoviridae, Parvoviridae, Herpesviridae, Poxviridae, Hepadnaviridae). 13. The most important representatives of RNA viruses (Picornaviridae, Caliciviridae and Astroviridae, Reoviridae, Matonaviridae, Flaviviridae, Coronaviridae). 14. The most important representatives of RNA viruses - continued (Paramyxoviridae, Rhabdoviridae, Filoviridae, Orthomyxoviridae, Retroviridae). Last update: Častorálová Markéta (15.09.2023)
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http://www.szu.cz/ https://www.ecdc.europa.eu/en https://www.cdc.gov/ https://www.who.int/ https://www.wikiskripta.eu/ Infekční lékařství Last update: Častorálová Markéta (15.09.2023)
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Students will:
Last update: Častorálová Markéta (15.09.2023)
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Microbiology, Biochemistry, Biology Last update: Ulbrich Pavel (23.01.2018)
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Teaching methods | ||||
Activity | Credits | Hours | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na zkoušku a její absolvování | 2 | 56 | ||
3 / 3 | 84 / 84 |