SubjectsSubjects(version: 956)
Course, academic year 2019/2020
Hygienic and clinical microbiology - M320018
Title: Hygienicko-klinická mikrobiologie
Guaranteed by: Department of Biochemistry and Microbiology (320)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2019 to 2019
Semester: winter
Points: winter s.:3
E-Credits: winter s.:3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: not taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Ulbrich Pavel doc. Ing. Ph.D.
Interchangeability : N320052
Examination dates   Schedule   
This subject contains the following additional online materials
Annotation -
In the course, students will learn about the different groups of pathogens, their most important representatives and the diseases caused by them. They will also learn the principles of prevention (vaccination) and treatment (antibiotics, antifungals, antiparasitics and antivirals) of infectious diseases. Attention will also be paid to the development of resistance. In selected cases, the basic principles and mechanisms of the life cycle of microorganisms will be described. Students will also be introduced to clinical microbiology laboratory methods.
Last update: Častorálová Markéta (15.09.2023)
Aim of the course -

Students will:

  • be able to characterize the most important causative agents of bacterial, yeast/fungal, viral and parasitic diseases
  • be able to assess the significance of individual pathogens in terms of clinical microbiology
  • know the effects of pathogenicity factors
  • know the mechanisms of action of antimicrobial agents and mechanisms of resistance
  • know the mechanisms involved in the prevention of microbial diseases (vaccination)
Last update: Častorálová Markéta (15.09.2023)
Literature -

A: Hurych, J.; et al. Lékařská mikrobiologie - repetitorium, 3.rd ed.; Triton: Praha, 2021. 978-80-7553-976-2

R: M. Votava a kol., Lékařská mikrobiologie speciální, Neptun, Brno, 2003, 80-902896-6-5

R: M. Votava, Lékařská mikrobiologie obecná, Neptun, Brno, 2005, 80-86850-00-5

R: M. Votava a kol., Lékařská mikrobiologie vyšetřovací metody, Neptun, Brno, 2010, 978-80-86850-04-8

Last update: Častorálová Markéta (15.09.2023)
Learning resources - Infekční lékařství

Last update: Častorálová Markéta (15.09.2023)
Syllabus -

1. Introduction. Historical development and importance of medical microbiology. Natural microbiota.

2. Antibiotics, their division, mechanisms of action, emergence of resistance. Basics of immunity. Vaccination, vaccines. Mandatory and recommended vaccinations, vaccination calendar.

3. Virulence factors of bacteria - mechanism, description and distribution, toxins.

4. Classification of bacteria and their diagnosis, culture media, procedure for obtaining samples and their processing.

5. Clinically important G+ cocci (Micrococcus, Staphylococcus, Streptococcus, Enterococcus) and rods (Listeria, Bacillus, Clostridium).

6. G-facultatively anaerobic rods (family Enterobacteriaceae, Vibrionaceae, Pasteurellaceae).

7. Other clinically important G- bacteria (Pseudomonas, Bordetella, Brucella, Francisella, Legionella, Helicobacter, Campylobacter, Neisseria).

8. Completion of clinically important G+ bacteria (Nocardia, Cutibacterium) and non-traditional G+ and G- bacteria (Mycobacterium, Mycoplasma, Chlamydia, Rickettsia, Bartonella). Spirochetes (Borrelia, Treponema).

9. Clinically important micromycetes (yeasts, fungi), mycotoxins, antifungals.

10. Clinically important parasites, antiparasitics.

11. Viruses - definition, history, classification of viruses. Diagnosis, vaccination, antivirals. Prions.

12. Representatives of DNA viruses (Papillomaviridae, Polyomaviridae, Adenoviridae, Parvoviridae, Herpesviridae, Poxviridae, Hepadnaviridae).

13. The most important representatives of RNA viruses (Picornaviridae, Caliciviridae and Astroviridae, Reoviridae, Matonaviridae, Flaviviridae, Coronaviridae).

14. The most important representatives of RNA viruses - continued (Paramyxoviridae, Rhabdoviridae, Filoviridae, Orthomyxoviridae, Retroviridae).

Last update: Častorálová Markéta (15.09.2023)
Registration requirements -

Microbiology, Biochemistry, Biology

Last update: Ulbrich Pavel (23.01.2018)
Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na zkoušku a její absolvování 2 56
3 / 3 84 / 84
Coursework assessment
Form Significance
Examination test 70
Oral examination 30