Subjects

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Biopharmaceuticals - M320021

Title:	Bioléčiva
Guaranteed by:	Department of Biochemistry and Microbiology (320)
Faculty:	Faculty of Food and Biochemical Technology
Actual:	from 2023 to 2025
Semester:	winter
Points:	winter s.:3
E-Credits:	winter s.:3
Examination process:	winter s.:
Hours per week, examination:	winter s.:2/0, Ex [HT]
Capacity:	unlimited / unknown (unknown)
Min. number of students:	unlimited
Qualifications:
State of the course:	taught
Language:	Czech
Teaching methods:	full-time
Level:
Note:	deregister from the exam date if a requisite was not fulfilled course can be enrolled in outside the study plan enabled for web enrollment

Guarantor:	Fusek Martin prof. Ing. CSc. Benešová Eva Ing. Ph.D.
Classification:	Chemistry > Biochemistry

Examination dates

This subject contains the following additional online materials

E-learning course

Annotation -

The subject "Biopharmaceuticals" is dedicated to a general description of rapidly developing field of pharmaceutical industry to the students. In the general part of the course, attention will be paid to the differences in the production of small molecules and proteins, after that different types of biodrugs (hormones, enzymes, cytokines, antibodies, vaccines and gene therapies) and their indications will be discussed.

Last update: Benešová Eva (28.04.2025)

Course completion requirements - Czech

Předmět je zakončen písemnou a ústní zkouškou.

Last update: Benešová Eva (28.04.2025)

Literature -

R:Fusek M., Káš J., Ruml T., Bioléčiva � VŠCHT Praha, 2008, 9788070806784

A:Fusek M., Vitek L, Blahos J., Hajdúch M., Ruml T., Biologická léčiva - teoretické základy a klinická praxe, GRADA, 2012, 9788024737270

A: Walsh G., Biopharmaceuticals - biochemistry and biotechnology, Wiley, 2003, 0470843268

Last update: Hladíková Jana (13.12.2017)

Requirements to the exam - Czech

Předmět je zakončen písemnou a ústní zkouškou.

Last update: Benešová Eva (28.04.2025)

Syllabus -

1. Biopharmaceuticals, history and the content of the subject

2. Biopharmaceuticals vs small molecules

3. Manufacturing aspects and methodology of biodrug analysis

4. Production organisms and their specifics

5.-6. Overview of main biodrugs - hormones

7. Overview of main biodrugs - cytokines

8.-9. Overview of main biodrugs - enzymes

10. Production of different types of antibodies (murine, chimeric, humanized, fully human, phage display)

11. Overview of main biodrugs - antibodies

12. Overview of main biodrugs - vaccines

13. Gene therapies

14. Invited lecture

Last update: Benešová Eva (28.04.2025)

Learning resources -

Lectures in electronic form published at e-learning.vscht.cz

Dictionary of Biopharmaceuticals and Fundamentals of Human Pathology available at e-learning.vscht.cz

Last update: Benešová Eva (28.04.2025)

Learning outcomes -

Students will get knowledge of

• basic processes for recombinant pharmaceuticals production

• main types of indications and pathologies in which biodrugs are applied

• main representatives = particular biodrugs

Last update: Benešová Eva (28.04.2025)

Registration requirements -

Biochemistry (Biochemistry I)

Molecular Genetics

Last update: Benešová Eva (28.04.2025)

Teaching methods
	Activity	Credits	Hours
	Účast na přednáškách	1	28
	Příprava na zkoušku a její absolvování	2	56
		3 / 3	84 / 84