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Last update: Hladíková Jana (13.12.2017)
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Last update: Hladíková Jana (13.12.2017)
Students will get knowledge of • basic processes for recombinant pharmaceuticals production • basic analytical procedures • main types of indications and pathologies in which biodrugs are applied • main representatives = particular biodrugs |
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Last update: Hladíková Jana (13.12.2017)
R:Fusek M., Káš J., Ruml T., Bioléčiva � VŠCHT Praha, 2008, 9788070806784 A:Fusek M., Vitek L, Blahos J., Hajdúch M., Ruml T., Biologická léčiva - teoretické základy a klinická praxe, GRADA, 2012, 9788024737270 A: Walsh G., Biopharmaceuticals - biochemistry and biotechnology, Wiley, 2003, 0470843268 |
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Last update: Hladíková Jana (13.12.2017)
www.sciencedirect.com |
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Last update: Kubová Petra Ing. (23.02.2018)
1. Biopharmaceuticals, history and the content of the subject 2. Biomacromolecules - structure, posttranslational modifications 3. Biomacromolecules - function 4. Analysis of biomacromolecules - methodology 5. Organisms used for biodrugs production and cell biology 6. Methods of fermentation - animal cell lines, genetic modifications 7. Isolation procedures - methodology 8. Overview of main biodrugs - monoclonal antibodies 9. Overview of main biodrugs - proteins and enzymes replacement therapy 10. Proteins and enzymes replacement therapy 11. Overview of main biodrugs -vaccines 12. Overview of main biodrugs - expression regulation and future prospects 13. Biodrugs safety and quality control 14. Commercial aspects - overview of main manufacturers and sales |
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Last update: Hladíková Jana (13.12.2017)
Biochemistry (Biochemistry I) Molecular Genetics |
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Last update: Fusek Martin prof. Ing. CSc. (15.01.2018)
Student musí úspěšně absolvovat závěrečný test a poté absolvovat úspěšně ústní zkoušku. |
Teaching methods | ||||
Activity | Credits | Hours | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na zkoušku a její absolvování | 2 | 56 | ||
3 / 3 | 84 / 84 |
Coursework assessment | |
Form | Significance |
Examination test | 25 |
Oral examination | 75 |