SubjectsSubjects(version: 955)
Course, academic year 2023/2024
Structure and Reactivity - M342002
Title: Struktura a reaktivita
Guaranteed by: Department of Chemistry of Natural Compounds (342)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2019
Semester: summer
Points: summer s.:4
E-Credits: summer s.:4
Examination process: summer s.:
Hours per week, examination: summer s.:2/1, C+Ex [HT]
Capacity: unlimited / unlimited (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Parkan Kamil doc. Ing. Ph.D.
Interchangeability : N342003
Annotation -
The subject is aimed at understanding basic principles and mechanisms in modern organic chemistry. Attention is given primarily to the structure of organic compounds and their reactivity which is a prerequisite for a deeper understanding of organic chemistry.
Last update: Kubová Petra (19.12.2017)
Aim of the course -

Students will be able to:

Understand the basics of molecular structure (AO, MO) and structure of organic compounds (isomers)

Assess reactivity of organic compounds (thermodynamics, kinetics)

Depict reaction mechanisms of principle organic reactions (nucleophilic substitution, addition, elimination, …)

Last update: Parkan Kamil (27.02.2018)
Literature -

R: Mark G. Moloney: Structure and Reactivity in Organic Chemisty, Wiley-Blackwell, 2008, 978-1405114516

A: McMurry J.: Organic chemistry, 8th Ed., Brooks/Cole, Cengage Learning, 2012, 9780840054449

Last update: Kubová Petra (19.12.2017)
Learning resources -

Lecture notes

Last update: Kubová Petra (19.12.2017)
Syllabus -

1. Valency (structure, covalent bond)

2. Structure (configuration, conformation)

3. Reactivity (thermodynamics, kinetics, …)

4. Intermediates (carbocations, carbanions, radicals, carbenes, benzynes, ketenes)

5. Acids and bases (Lowry-Brønsted theory)

6. Nucleophilic substitution (SN1 reaction, SN2 reaction, synthetic applications)

7. Addition reactions (AE, AN, addition of ketenes, synthetic applications)

8. Elimination reactions (elimination, oxidation processes, …)

9. Aromatic substitution (aromaticity, reactions)

10. Stepwise addition and elimination reactions (addition-elimination reaction, metathesis, …)

11. Radical reactions (radical generation, subsequent reactions)

12. Coupling reactions (Pd-catalyzed reactions, reactions catalyzed by other elements)

13. Pericyclic reactions (molecular orbitals, pericyclic reactions, synthetic applications)

14. Aldol reaction and condensation, Claisen reaction, conjugate addition reaction

15. Types of non-covalent bonds (hydrogen bond in bioorganic molecules, …)

Last update: Parkan Kamil (26.08.2020)
Registration requirements -

Organic chemistry I, or Organic chemistry A and B

Last update: Parkan Kamil (27.02.2018)
Course completion requirements

Napsání započtového testu, zkouškového testu a ústní zkouška.

Last update: Parkan Kamil (27.02.2018)
Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 1 28
Účast na seminářích 1 28
4 / 4 112 / 112