SubjectsSubjects(version: 954)
Course, academic year 2019/2020
NMR Spectroscopy in Natural Compounds - M342008
Title: NMR pro studium přírodních látek
Guaranteed by: Department of Chemistry of Natural Compounds (342)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2019 to 2022
Semester: summer
Points: summer s.:3
E-Credits: summer s.:3
Examination process: summer s.:
Hours per week, examination: summer s.:2/1, MC [HT]
Capacity: unlimited / unlimited (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Additional information: http://doc. Ing. R. Hrabal, CSc.
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Hrabal Richard prof. Ing. CSc.
Dvořáková Hana Ing. CSc.
Prchal Jan Ing. Ph.D.
Interchangeability : N342010
Examination dates   Schedule   
This subject contains the following additional online materials
Annotation -
The purpose of the course is to teach students the fundaments of Nuclear magnetic resonance spectroscopy. It is designed for NMR users to be able to use NMR spectroscopy for the solution of their own scientific projects, i.e. to choose a proper NMR experiment, to set it up on an NMR spectrometer, process the results and interpret the spectra. The course is divided into three sections, the first one is about physical background of NMR, the second one is devoted to the interpretation of NMR spectra and the last one should help students to orient themselves in numerous applications of NMR spectroscopy. Students must work out their own projects to be able to pass the course.
Last update: Hrabal Richard (24.01.2018)
Aim of the course -

Students will be able to:

Understand the basics of NMR spectroscopy and its cpacity for solving common problems in chemists’ practice

Set up simple 1D and 2D experiments on an NMR spectrometer

Process NMR data

Interpret NMR spectra

Last update: Hrabal Richard (24.01.2018)
Literature -

R: H. Friebolin: Basic One- and Two-Dimensional NMR Spectroscopy, Wiley-VCH, 4. edition, 2005

A: H. Günther: NMR Spectrsocopy John Wileay and Sons, 2.edition, 2001

Last update: Hrabal Richard (24.01.2018)
Learning resources -

Last update: Hrabal Richard (24.01.2018)
Syllabus -

1. Basic concepts, principle of pulse experiments

2. Two- and multidimensional NMR

3. Nuclear relaxation, chemical exchange, NOE effect

4. Construction and basis of operation of NMR spectrometers

5. Interpretation of NMR spectra, calculations, databases

6. Conformational analysis I

7. Conformational analysis II

8. Chemical exchange

9. Multi-nuclear NMR and its application for solving particular problems

10. Examination project assignment

11. NMR of biologically active systems

12. Study of non-bonding interactions

13. Quantitative NMR, magnetic resonance imaging

14. Solid-state NMR

Last update: Kubová Petra (19.12.2017)
Registration requirements -

Basic knowledge of mathematics, physics, and chemistry

Last update: Kubová Petra (19.12.2017)
Course completion requirements -

The course is completed by a written exam. There is an option to improve the grade by an oral exam.

Last update: Hrabal Richard (26.01.2018)
Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0.2 5
Obhajoba individuálního projektu 0.4 10
Účast na přednáškách 1 28
Příprava na zkoušku a její absolvování 0.9 25
Účast na seminářích 0.5 14
3 / 3 82 / 84
Coursework assessment
Form Significance
Defense of an individual project 25
Examination test 50
Oral examination 25