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The search for new pharmaceuticals using knowledge of biological objectives is a complex matter. This course is focused on the chemical nature of this problem.
Last update: Pátková Vlasta (05.01.2018)
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Zkouška probíhá formou písemné i ústní zkoušky. Last update: Vosmanská Magda (21.02.2018)
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R: http://www.vscht.cz/kot/cz/studijni-materialy.html R: http://www.alga.cz/users/tichym/AMB/12_drugdiscovery.ppt R: http://www.cc.nih.gov/training/training/principles/slides/DrugDevProgram08-09oneslide.pdf A: http://mediaserver.aapspharmaceutica.com/meetings/DDS/Integration%20of%20In%20Silico%20Models%20in%20Drug%20Design.pdf A: http://pharm.swu.ac.th/web_npec/content/JOURNAL/LectureAutoDock.pdf A: http://www.cc.nih.gov/training/training/principles/slides/DrugDevProgram08-09oneslide.pdf Last update: Pátková Vlasta (05.01.2018)
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1.The identification of biological target. 2.The targeting of drugs on proteins. 3.The targeting of drugs on DNA. 4.Other biological targets. 5.Drug Design: computational methods. 6.Molecular modeling, Docking. 7.Design of anti-cancer agents by function and target biological structure. 8.Cytostatics. 9.Design of anti-virals. 10.Antivirals I. 11.To provide drugs for CNS. 12.To provide drugs for CVS. 13.Natural substances such as structural elements for modern pharmaceuticals I. 14.Natural substances such as structural elements for modern pharmaceuticals II. Last update: Pátková Vlasta (05.01.2018)
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http://www.vscht.cz/kot/cz/studijni-materialy.html Last update: Pátková Vlasta (05.01.2018)
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Students will be able to apply a variety of techniques to address the problems associated with the emergence of new medicines. Last update: Pátková Vlasta (05.01.2018)
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None. Last update: Pátková Vlasta (05.01.2018)
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Teaching methods | ||||
Activity | Credits | Hours | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi | 0.3 | 8 | ||
Příprava na zkoušku a její absolvování | 1.7 | 48 | ||
3 / 3 | 84 / 84 |