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Last update: Dvořák Dalimil prof. Ing. CSc. (28.04.2005)
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Last update: Cibulka Radek prof. Ing. Ph.D. (19.08.2013)
Students will be able to: distinguish basic types of reactions which occur in the coordination sphere of transition metals understand the mechanisms of transition metals catalyzed reactions which are used in organic synthesis propose synthesis of organic compounds using chemistry of transition metals |
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Last update: Dvořák Dalimil prof. Ing. CSc. (23.07.2013)
R:L. S. Hegedus: Transition Metals in the Synthesis of Complex Organic Molecules (University Science Books, Sausalito, California, 1999), 1891389041 A:Skripta: D. Dvořák: Chemie organokovových sloučenin přechodných kovů (VŠCHT 1993), 80-7080-209-X |
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Last update: Dvořák Dalimil prof. Ing. CSc. (23.07.2013)
Dalimil Dvořák: Chemie organokovových sloučenin přechodných kovů: http://uoch.vscht.cz/cz/download/metalika.pdf |
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Last update: Dvořák Dalimil prof. Ing. CSc. (28.04.2005)
1. Formalism (oxidation state, d-electron configuration, 18-electron rule). 2. Basic types of ligands (s-complexes). 3. Basic types of ligands (p-complexes). 4. Reactions in coordination sphere of transition metals (ligand substitution, oxidative addition, reductive elimination, insertion, transmetallation). 5. Nucleophilic attack on ligands coordinated to transition metals. 6. Electrophilic attack on ligands coordinated to transition metals. 7. Homogeneous catalytic reactions (hydrogenation, hydrosilation, hydrocyanation, alkene and alkyne polymerisation, carbonylation reactions). 8. Synthetic applications of transition metal hydrides, organocuprates. 9. Synthetic applications of complexes from insertion of alkenes and alkynes. 10. Synthetic applications of complexes from oxidative addition followed with insertion of alkene, alkyne and carbon monoxide (cross coupling, Heck reaction). 11. Synthetic applications of transition metal carbonyl complexes. 12. Synthetic applications of transition metal carbene complexes (reactions of nucleophilic and electrophilic carbenes, alkene metathesis, metal-catalysed decomposition of diazo compounds). 13. Synthetic applications of h3-allyl transition metal complexes. 14. Synthetic applications of transition metal h6-arene complexes (Cr(CO)3 and FeCp+ complexes). |
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Last update: Dvořák Dalimil prof. Ing. CSc. (23.07.2013)
Organic synthesis, Mechanisms of organic reactions |
Teaching methods | ||||
Activity | Credits | Hours | ||
Účast na přednáškách | 1.5 | 42 | ||
Příprava na zkoušku a její absolvování | 4 | 112 | ||
Účast na seminářích | 0.5 | 14 | ||
6 / 6 | 168 / 168 |
Coursework assessment | |
Form | Significance |
Continuous assessment of study performance and course -credit tests | 50 |
Oral examination | 50 |