SubjectsSubjects(version: 855)
Course, academic year 2019/2020
  
Biotechnology in Chemical and Pharmaceutical Industry - N319035
Title: Biotechnologie v chemické a farmaceutické výrobě
Guaranteed by: Department of Biotechnology (319)
Actual: from 2012
Semester: winter
Points: winter s.:5
E-Credits: winter s.:5
Examination process: winter s.:
Hours per week, examination: winter s.:2/2 C+Ex [hours/week]
Capacity: 35 / 35 (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Level:  
For type:  
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Masák Jan prof. Ing. CSc.
This subject contains the following additional online materials
Annotation -
Last update: TAJ319 (11.12.2013)
Chemical and pharmaceutical industry extends the use of biotechnological processes for obtaining new compounds or for reducing costs and environmental impact of the production of current compounds. Introductory lectures will provide detailed information about the current range of implementation of biotechnological processes in these industries. Attention is also given to explain the procedures for development of industrial strains achieving the high production of required compounds. The various types of processes are then discussed using examples of production of particular substances applied in the chemical and pharmaceutical industries. Special attention is paid to biotransformation processes. In the seminar, students work out individual theme the output of which is the design of a biotechnological process for the production of a selected substance.
Aim of the course -
Last update: Masák Jan prof. Ing. CSc. (30.08.2013)

Students will be able to:

select appropriate procedures for the preparation of industrial biological agents (microorganisms, enzymes, plant or animal tissue culture);

generally suggest biotechnological process for the production a substance;

evaluate the process, health and economic risks of a particular biotechnology;

apply extensive knowledge in the design of biotechnological processes in the chemical and biotechnology industries

Literature -
Last update: TAJ319 (30.08.2013)

R:Moo-Young, M:Comprehensive Biotechnology (2nd ed.), Elsevier, Amsterdam, 2011,9780080885049

A:Rehm,H.-J.,Reed G.: Biotechnology, 12 Vols., 2nd Ed, Wiley, Weinheim, 2008,9783527620821

A:Flickinger, M.C.: Encyclopedia of Bioprocess Technology, Wiley, 2008,9780471250586

A:Ho, R.J.Y: Biotechnology and Biopharmaceuticals, Wiley, 2003,0471206903

Learning resources -
Last update: Masák Jan prof. Ing. CSc. (30.08.2013)

http://eso.vscht.cz/

Syllabus -
Last update: Masák Jan prof. Ing. CSc. (30.08.2013)

1. Introduction - the status of biotechnology in the chemical and pharmaceutical industry

2. Characteristics of biotechnological processes

3. The development of industrial strains - physiological adaptation, gene modification, transformation of higher organisms

4. Biotechnological production of primary and secondary metabolites - unit operations, process management, economic balance

5. Biotechnological production of biopharmaceuticals - characteristics of the processes

6. Biotransformation - basic characteristics of the processes

7. Biotransformation - examples

8. Antibiotics - characteristics, production organisms, technological processes

9. Antibiotics - the current state of world production, research and development

10. Cancerostatics - characteristics, production organisms, technological processes

11. Alkaloids - characteristics, production organisms, technological processes

12. Vitamins - characteristics, production organisms, technological processes

13. Enzymes - characteristics, production organisms, technological processes

14. Polysaccharides - characteristics, production organisms, technological processes

Registration requirements -
Last update: Masák Jan prof. Ing. CSc. (30.08.2013)

Biochemistry, Microbiology, Bioengineering

Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0,3 7
Obhajoba individuálního projektu 0,3 7
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 0,5 14
Práce na individuálním projektu 0,9 26
Příprava na zkoušku a její absolvování 1 28
Účast na seminářích 1 28
5 / 5 138 / 140
Coursework assessment
Form Significance
Regular attendance 30
Defense of an individual project 20
Report from individual projects 10
Oral examination 40

 
VŠCHT Praha