SubjectsSubjects(version: 955)
Course, academic year 2021/2022
Biotechnology in Chemical and Pharmaceutical Industry - N319035
Title: Biotechnologie v chemické a farmaceutické výrobě
Guaranteed by: Department of Biotechnology (319)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2021
Semester: winter
Points: winter s.:5
E-Credits: winter s.:5
Examination process: winter s.:
Hours per week, examination: winter s.:2/2, C+Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: cancelled
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Is provided by: M319017
Guarantor: Masák Jan prof. Ing. CSc.
Is interchangeable with: M319017
Examination dates   Schedule   
Annotation -
Chemical and pharmaceutical industry extends the use of biotechnological processes for obtaining new compounds or for reducing costs and environmental impact of the production of current compounds. Introductory lectures will provide detailed information about the current range of implementation of biotechnological processes in these industries. Attention is also given to explain the procedures for development of industrial strains achieving the high production of required compounds. The various types of processes are then discussed using examples of production of particular substances applied in the chemical and pharmaceutical industries. Special attention is paid to biotransformation processes. In the seminar, students work out individual theme the output of which is the design of a biotechnological process for the production of a selected substance.
Last update: TAJ319 (11.12.2013)
Aim of the course -

Students will be able to:

select appropriate procedures for the preparation of industrial biological agents (microorganisms, enzymes, plant or animal tissue culture);

generally suggest biotechnological process for the production a substance;

evaluate the process, health and economic risks of a particular biotechnology;

apply extensive knowledge in the design of biotechnological processes in the chemical and biotechnology industries

Last update: Masák Jan (30.08.2013)
Literature -

R:Moo-Young, M:Comprehensive Biotechnology (2nd ed.), Elsevier, Amsterdam, 2011,9780080885049

A:Rehm,H.-J.,Reed G.: Biotechnology, 12 Vols., 2nd Ed, Wiley, Weinheim, 2008,9783527620821

A:Flickinger, M.C.: Encyclopedia of Bioprocess Technology, Wiley, 2008,9780471250586

A:Ho, R.J.Y: Biotechnology and Biopharmaceuticals, Wiley, 2003,0471206903

Last update: TAJ319 (30.08.2013)
Learning resources -

Last update: Masák Jan (30.08.2013)
Syllabus -

1. Introduction - the status of biotechnology in the chemical and pharmaceutical industry

2. Characteristics of biotechnological processes

3. The development of industrial strains - physiological adaptation, gene modification, transformation of higher organisms

4. Biotechnological production of primary and secondary metabolites - unit operations, process management, economic balance

5. Biotechnological production of biopharmaceuticals - characteristics of the processes

6. Biotransformation - basic characteristics of the processes

7. Biotransformation - examples

8. Antibiotics - characteristics, production organisms, technological processes

9. Antibiotics - the current state of world production, research and development

10. Cancerostatics - characteristics, production organisms, technological processes

11. Alkaloids - characteristics, production organisms, technological processes

12. Vitamins - characteristics, production organisms, technological processes

13. Enzymes - characteristics, production organisms, technological processes

14. Polysaccharides - characteristics, production organisms, technological processes

Last update: Masák Jan (30.08.2013)
Registration requirements -

Biochemistry, Microbiology, Bioengineering

Last update: Masák Jan (30.08.2013)
Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0.3 7
Obhajoba individuálního projektu 0.3 7
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 0.5 14
Práce na individuálním projektu 0.9 26
Příprava na zkoušku a její absolvování 1 28
Účast na seminářích 1 28
5 / 5 138 / 140
Coursework assessment
Form Significance
Regular attendance 30
Defense of an individual project 20
Report from individual projects 10
Oral examination 40