SubjectsSubjects(version: 955)
Course, academic year 2023/2024
Biophysical Chemistry - N320021
Title: Biofyzikální chemie
Guaranteed by: Department of Biochemistry and Microbiology (320)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2021
Semester: both
Points: 3
E-Credits: 3
Examination process:
Hours per week, examination: 2/0, Ex [HT]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: cancelled
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Is provided by: M320001
Additional information: http://předmět je vyučován pouze v zimním semestru
Note: you can enroll for the course in winter and in summer semester
Guarantor: Holík Purkrtová Zita Ing. Ph.D.
Marková Michaela Ing. Ph.D.
Interchangeability : M320001
Is interchangeable with: M320001
Examination dates   Schedule   
Annotation -
The lectures are focused on description of physical-chemical aspects of biological systems and use of physical-chemical terms to describe and solve the problems in biological systems. Students will have an overview of the most important concepts and methodology of modern biophysical chemistry as well as structural methods for description of biomacromolecules.
Last update: Marková Michaela (14.11.2012)
Aim of the course -

Students will be able to:

Describe basic biochemical processes by mathematical methods used in physical chemistry.

Apply the principles of physical chemistry in interpretation and solving problems occuring in biological systems. The problems solution includes numerical analysis of chosen physical chemistry parameters.

Independently propose a method and design a protocol for experimental determination of chosen physical chemistry parameters in biological systems and analyse obtained data.

Last update: Holík Purkrtová Zita (16.07.2013)
Literature -

R: Atkins P.,de Paula J., Physical Chemistry for the Life Sciences, Oxford University Press, 2011, 978-0-19-956428-6

R: Bergethon P.R., The Physical Basis of Biochemistry, Springer-Verlag New York Inc., 1998, 0-387-98262-0

A: Nelson D.L., Cox M.M., Lehninger Principles of Biochemistry, W.H.Freeman, 2008, 978-0716771081

Last update: Holík Purkrtová Zita (16.07.2013)
Learning resources -

Last update: Holík Purkrtová Zita (16.07.2013)
Syllabus -

1. Position of biophysical chemistry in the system of natural science

2. Bioenergetics I

3. Bioenergetics II (non-equilibrium thermodynamics)

4. The importance of noncovalent interactions for biological systems

5. The general characteristics of protein structure

6. Methods of kinetics measurement of biological processes

7. Pharmacokinetics

8. Structure and function of biological membranes

9. Biological processes associated with membranes: biochemistry of vision, electron transport chain and photosynthesis

10. Electrochemical processes in biological systems

11. The use of spectrophotometry in biochemical laboratory

12. The use of radiochemistry for the study of biological processes

13. Methods for the study of protein structure I: NMR and X-ray crystallography

14. Methods for the study of protein structure II: circular dichroism and fluorescence spectroscopy

Last update: Holík Purkrtová Zita (13.11.2012)
Registration requirements -


Physical chemistry

Last update: Holík Purkrtová Zita (16.07.2013)
Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0.2 5
Účast na přednáškách 1 28
Příprava na zkoušku a její absolvování 1.8 51
3 / 3 84 / 84
Coursework assessment
Form Significance
Examination test 60
Oral examination 40