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The lectures are focused on description of physical-chemical aspects of biological systems and use of physical-chemical terms to describe and solve the problems in biological systems. Students will have an overview of the most important concepts and methodology of modern biophysical chemistry as well as structural methods for description of biomacromolecules.
Last update: Marková Michaela (14.11.2012)
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R: Atkins P.,de Paula J., Physical Chemistry for the Life Sciences, Oxford University Press, 2011, 978-0-19-956428-6 R: Bergethon P.R., The Physical Basis of Biochemistry, Springer-Verlag New York Inc., 1998, 0-387-98262-0 A: Nelson D.L., Cox M.M., Lehninger Principles of Biochemistry, W.H.Freeman, 2008, 978-0716771081 Last update: Holík Purkrtová Zita (16.07.2013)
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1. Position of biophysical chemistry in the system of natural science 2. Bioenergetics I 3. Bioenergetics II (non-equilibrium thermodynamics) 4. The importance of noncovalent interactions for biological systems 5. The general characteristics of protein structure 6. Methods of kinetics measurement of biological processes 7. Pharmacokinetics 8. Structure and function of biological membranes 9. Biological processes associated with membranes: biochemistry of vision, electron transport chain and photosynthesis 10. Electrochemical processes in biological systems 11. The use of spectrophotometry in biochemical laboratory 12. The use of radiochemistry for the study of biological processes 13. Methods for the study of protein structure I: NMR and X-ray crystallography 14. Methods for the study of protein structure II: circular dichroism and fluorescence spectroscopy Last update: Holík Purkrtová Zita (13.11.2012)
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http://biomikro.vscht.cz/vyuka/?Predmet=bfc Last update: Holík Purkrtová Zita (16.07.2013)
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Students will be able to: Describe basic biochemical processes by mathematical methods used in physical chemistry. Apply the principles of physical chemistry in interpretation and solving problems occuring in biological systems. The problems solution includes numerical analysis of chosen physical chemistry parameters. Independently propose a method and design a protocol for experimental determination of chosen physical chemistry parameters in biological systems and analyse obtained data. Last update: Holík Purkrtová Zita (16.07.2013)
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Biochemistry Physical chemistry Last update: Holík Purkrtová Zita (16.07.2013)
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Teaching methods | ||||
Activity | Credits | Hours | ||
Konzultace s vyučujícími | 0.2 | 5 | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na zkoušku a její absolvování | 1.8 | 51 | ||
3 / 3 | 84 / 84 |
Coursework assessment | |
Form | Significance |
Examination test | 60 |
Oral examination | 40 |