SubjectsSubjects(version: 949)
Course, academic year 2021/2022
Pathobiochemistry II - N320031
Title: Pathobiochemie II
Guaranteed by: Department of Biochemistry and Microbiology (320)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2021
Semester: summer
Points: summer s.:3
E-Credits: summer s.:3
Examination process: summer s.:
Hours per week, examination: summer s.:2/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Is provided by: M320007
For type:  
Guarantor: Šebesta Ivan MUDr. CSc.
Is interchangeable with: M320007
Examination dates   Schedule   
Annotation -
Last update: Šebesta Ivan MUDr. CSc. (10.02.2017)
The goal of the subject is to acquire basic pathobiochemistry processes in the human body. The course emphasizes a comprehensive explanation of the mechanisms of disease development at the level of tissues, cells and molecular biology,too. Students are also acquainted with effective indication and interpretation of basic biochemical tests. ) The latest research findings and treatment of diseases with high frequency (lifestyle diseases) are also presented.
Aim of the course -
Last update: Šebesta Ivan MUDr. CSc. (10.02.2017)

Students will able to:

get knowledge of pathobiochemistry mechanisms of disease development.

correctly interpret basic clinical biochemistry tests in their future practice.

Literature -
Last update: Šebesta Ivan MUDr. CSc. (10.02.2017)

R:Masopust J., Patobiochemie buňky. ČSKB, 2.LF UK, 2003, 80-239-1011-0

R:Masopust J., PrůšaR., Patobiochemie metabolických drah, 2.LFUK, 1999, 80-238-4589-6

R:Kalousová M. a kol., Patobiochemie ve schématech, Grada Publishing, 2006, 80-247-1522-8

R:Racek J. a kol., Klinická biochemie.2.vydání, Praha, Galén, Karolinum, 2006, 80-7262-324-9

R:Štern P. a kol., Obecná a klinická biochemie, Karolinum, Praha 2011, 978-80-246-1979-8

R:Karlson P., Gerok W., Gross W., Pathobiochemie, Academia, Praha 1987 (nemá ISBN)

A: Zima T. ed. Laboratorní diagnostika, druhé doplněné a přepracované vydání, Praha, Galén, 2007, 978-80-7262-372-3(Galén), 978-80-246-1423-6 (Karolinum)

Learning resources -
Last update: Šebesta Ivan MUDr. CSc. (10.02.2017)

Syllabus -
Last update: Šebesta Ivan MUDr. CSc. (10.02.2017)

1.Urine and pathobiochemistry of renal functions

2.Acid-base balance

3.Pathobiochemistry of connective tissue and bones

4.Pathobiochemistry of nervous and muscle tissue

5.Principles of hormonal regulation and its disorders,axis of hypothalamus and hypophysis

6.Adrenal cortex hormones and sex hormones

7.Thyroid and parathyroid hormones

8.Pathobiochemistry of malabsorption

9.Endocrine and exocrine pancreas

10.Biochemistry of malignant tumor

11.Biochemistry of inflammation

12.Vitamins, hypo- and hypervitaminosis

13.Xenobiochemistry and biotransformation of drugs


Registration requirements -
Last update: Šebesta Ivan MUDr. CSc. (10.02.2017)

Biochemistry I, Biochemistry II

Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 1 28
3 / 3 84 / 84
Coursework assessment
Form Significance
Regular attendance 10
Oral examination 90