SubjectsSubjects(version: 947)
Course, academic year 2021/2022
Hygienic and Clinical Microbiology - N320052
Title: Hygienicko-klinická mikrobiologie
Guaranteed by: Department of Biochemistry and Microbiology (320)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2021
Semester: winter
Points: winter s.:3
E-Credits: winter s.:3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
For type:  
Guarantor: Ulbrich Pavel doc. Ing. Ph.D.
Is interchangeable with: M320018
Examination dates   Schedule   
Annotation -
Last update: Ulbrich Pavel doc. Ing. Ph.D. (01.08.2013)
The course focuses on discrete groups of pathogenic microorganisms, the most important members of each group and their influence on human health. Students will also learn about the principles of antimicrobials and about the defence of microorganisms against these compounds. The attention will be paid to modern trends in protecting people against pathogens. On selected cases the mechanisms and prinicples of pathogenic microorganisms actions will be presented. In this course, students will also get acquainted with modern clinical microbiological laboratory methods.
Aim of the course -
Last update: Ulbrich Pavel doc. Ing. Ph.D. (01.08.2013)

Students will be able to:

Distinguish between the members of normal and pathogenic human microflora

Characterize the most important pathogens causing bacterial, fungal, viral and parasitic diseases

Evaluate the importance of selected microorganisms from the clinical microbiology point of view, together with their pathogenicity and pathogenesis of caused diseases

Discuss the mechanisms of antimicrobial agents actions and microbial-caused diseases prevention.

Literature -
Last update: Ulbrich Pavel doc. Ing. Ph.D. (01.08.2013)

R: M. Votava a kol., Lékařská mikrobiologie speciální, Neptun, Brno, 2003, 80-902896-6-5

A: M. Votava, Lékařská mikrobiologie obecná, Neptun, Brno, 2005, 80-86850-00-5

A: M. Votava a kol., Lékařská mikrobiologie vyšetřovací metody, Neptun, Brno, 2010, 978-80-86850-04-8

Learning resources -
Last update: Ulbrich Pavel doc. Ing. Ph.D. (01.08.2013)

Syllabus -
Last update: Ulbrich Pavel doc. Ing. Ph.D. (01.08.2013)

1.History and importance of medical microbiology. Basic concepts associated with clinical microbiology. Cultivation media. Physiological flora, pathogenic and facultatively pathogenic microorganisms - a general overview.

2. Pathogenicity and virulence of bacteria. Routes of infection in the body, the adhesion of bacteria, tropism. Types of infections and their spread, the incubation period. Toxins, their distribution and function.

3. Antibiotics, classification, mechanisms of action, the emergence of resistance. Multiresistance. Spirochetes (Treponema, Leptospira, Borrelia).

4. Clinically significant Gram-positive cocci (Micrococcus, Staphylococcus, Streptococcus, Enterococcus), Gram-negative cocci and coccobacilli - Neisseria, etc. Gram-positive non-spore forming and sporulating aerobic rods (Listeria, Bacillus).

5. Anaerobic bacteria (important representatives of G+ and G- bacilli and cocci). Non Gram-dyeable bacteria (Mycobacterium, Nocardia). Mollicutes - representatives and diseases. Chlamydia - representatives and diseases.

6. Non spore-forming aerobic bacteria (Corynebacterium, Arcanobacter, Rhodococcus, Rothia). Gram-positive aerobic spore-forming rods - Clostridium. Aerobic gram-negative rods (Pseudomonas, Legionella, Chryseobacterium, Alcaligenes, Brucella, Francisella, Bordetella).

7. Facultative anaerobic gram-negative rods (Enterobacteriaceae). Gram-negative aerobic to microaerophilic rods (Helicobacter, Campylobacter). Rickettsia (Rickettsia, Coxiella, Ehrlichia, Rochalimaea, Bartonella).

8. Fungi - classification, epidemiology and diseases caused by fungi. Surface, subcutaneous and systemic mycoses.

9. General parasitology, protozoa. Parasitic annelids and arthropods.

10. Viruses - definition, history. The main groups of viruses, classification of viruses. Viral infection. Bacteriophages.

11. Selected representatives of animal DNA viruses (Poxviridae, Herpesviridae, Adenoviridae, Papovaviridae, Hepadnaviridae, Parvoviridae).

12. The most important representatives of RNA viruses (Orthomyxoviridae, Paramyxoviridae, Picornaviridae, Caliciviridae and Astroviridae, Reoviridae, Coronaviridae, Bunyaviridae, Togaviridae, Arenaviridae, Rhabdoviridae, Filoviridae, Retroviridae).

13. The causative agents of viral hepatitis. Prions and prion diseases.

14. Vaccination, vaccines, prinicples. Mandatory and recommended vaccinations.

Registration requirements -
Last update: Ulbrich Pavel doc. Ing. Ph.D. (01.08.2013)

Microbiology, Biochemistry, Biology

Teaching methods
Activity Credits Hours
Účast na přednáškách 1 28
Příprava na zkoušku a její absolvování 2 56
3 / 3 84 / 84
Coursework assessment
Form Significance
Regular attendance 10
Examination test 45
Oral examination 45