Bioengineering - N320069
Title: Bioinženýrství
Guaranteed by: Department of Biochemistry and Microbiology (320)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2019 to 2021
Semester: winter
Points: winter s.:3
E-Credits: winter s.:3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: not taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Kaštánek Petr doc. Ing. Ph.D.
Interchangeability : N319008
Examination dates   Schedule   
Annotation -
The course focuses on understanding and quantitative description of biological processes in the context of their implementation under defined conditions enabling to achieve reproducibility of results. The syllabus is based on the principles of kinetics, balancing as well as measurement and regulation of biological processes, including the design of the equipment.
Last update: TAJ320 (11.12.2013)
Aim of the course -

Students will be able to:

Understand the biological, chemical and engineering processes in the biotechnology industry

Describe and evaluate basic biocatalytic processes.

Quantitatively evaluate experimental data of processes catalyzed by biological elements and to carry out heat and mass balances of biotechnological processes.

Design mixing and aeration equipment of bioreactors.

Last update: Brányik Tomáš (22.08.2013)
Literature -

R: Doran P.M.: Bioprocess Engineering Principles, Academic, London, 1995, ISBN: 9780122208553

R: Moo-Young M.: Comprehensive biotechnology, Elsevier B.V., 2011, ISBN: 9780080885049

A: Dunn I.J. et al.: Biological Reaction Engineering, Wiley-VCH, 2003, ISBN:9783527307593

A: Najafpour G.D.: Biochemical Engineering and Biotechnology, Elsevier B.V., 2007, ISBN 9780444528452

Last update: Brányik Tomáš (22.08.2013)
Learning resources -

Last update: Brányik Tomáš (22.08.2013)
Syllabus -

1. Engineering aspects of biotechnological processes

2. The structure of bioprocesses, overview of equipment and unit operations

3. Bioreactors - characteristics and types, methods of cultivation

4. Mixing in bioreactors - theory, power consumption, homogenization, shear stress

5. Hydrodynamic flow characteristics - retention time distribution, models of flow

6. Mass transfer - oxygen transfer, aeration methods, measurement and quantification, KLa

7. Heat transfer, heat balance of bioreactor, sterilization, cooling and heating

8. Engineering kinetics of chemical and enzymatic reactions

9. Kinetics of cell growth - mass balance, yield, metabolic quotient, inhibition, productivity

10. Cell culture methods - batch and fed batch cultivation

11. Cell culture methods - continuous culture

12. Scale-up and scale-down of bioprocesses

13. Measurement, control and modeling of biological processes

14. Design and construction of bioreactors, SIP and CIP systems

Last update: Brányik Tomáš (22.08.2013)
Registration requirements -

Chemical engineering, Microbiology

Last update: Brányik Tomáš (22.08.2013)
Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0.4 11
Obhajoba individuálního projektu 0.1 3
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 0.4 11
Práce na individuálním projektu 0.5 14
Příprava na zkoušku a její absolvování 0.6 17
3 / 3 84 / 84
Coursework assessment
Form Significance
Regular attendance 10
Report from individual projects 10
Examination test 20
Oral examination 60