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Last update: Matějka Pavel prof. Dr. RNDr. (31.08.2013)
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Last update: Matějka Pavel prof. Dr. RNDr. (31.08.2013)
Students will be able to: Explain principles of spectrometric and diffractometric methods used for structural analysis. Describe experimental techniques which are appropriate for structural analysis for various types of pharmaceutical formulations. Interpret experimental data for simple organic compounds with possible applications in pharmacy. |
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Last update: VED402 (01.10.2013)
R:Moderní přístupy k farmaceutické analýze 2; Strukturní analýza léčiv, Dohnal J. a kol., Brno: Veterinární a farmaceutická univerzita Brno, 2009, ISBN: 978-80-7305-058-0. A:NMR Spectroscopy in Pharmaceutical Analysis, Edited by: Holzgrabe, Ulrike; Wawer, Iwona; Diehl, Bernd; 2008 Elsevier, ISBN: 978-0-444-53173-5, Electronic ISBN: 978-0-0805-5819-6 A:Structure Determination of Organic Compounds - Tables of Spectral Data (3rd Edition), By: Pretsch, E., Bühlmann, P., Affolter, C.; 2000 Springer - Verlag, ISBN: 978-3-540-67815-1, Electronic ISBN: 978-1-60119-351-3 A:Crystal Structure Determination, By Massa, Werner, 2nd ed., 2004, Springer, ISBN: 978-3-540-20644-6 A:Structure Determination from Powder Diffraction Data (International Union of Crystallography Monographs on Crystallography) By W.I.F. David, K. Shankland, L.B. McCusker, and C. Bärlocher, OUP Oxford; New Ed edition Aug 2006, ISBN: 978-0199205530 |
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Last update: Matějka Pavel prof. Dr. RNDr. (31.08.2013)
electronic materials - lecture slides - available in the domain vscht.cz |
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Last update: Matějka Pavel prof. Dr. RNDr. (31.08.2013)
1. Classes of methods of structural analysis 2. X-ray diffractometry - principles of the method 3. X-ray diffractometry - instrumentation 4. Analysis and evaluation of diffractograms 5. X-ray diffractometry - application in pharmaceutical analysis 6. NMR spectrometry - principles of the method 7. NMR spectrometry - analysis of solutions 8. NMR spectrometry - analysis of solids 9. Vibrational spectrometry - principles 10.Infrared spectrometry and structure of substances 11.Raman spectrometry and structure of substances 12.Infrared and Raman microspectrometry - mapping and imaging 13.Mass spectrometry and structure of chemical substances 14.Combination of methods of structural analysis - complex interpretation |
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Last update: Matějka Pavel prof. Dr. RNDr. (31.08.2013)
Introduction to spectral methods of drug analysis |
Teaching methods | ||||
Activity | Credits | Hours | ||
Konzultace s vyučujícími | 0.5 | 14 | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na zkoušku a její absolvování | 1.5 | 42 | ||
3 / 3 | 84 / 84 |
Coursework assessment | |
Form | Significance |
Regular attendance | 10 |
Examination test | 60 |
Oral examination | 30 |