SubjectsSubjects(version: 963)
Course, academic year 2024/2025
  
Advanced separation methods for drug analysis - N402064
Title: Pokročilé separační metody analýzy léčiv
Guaranteed by: Department of Analytical Chemistry (402)
Faculty: Faculty of Chemical Engineering
Actual: from 2019
Semester: winter
Points: winter s.:5
E-Credits: winter s.:5
Examination process: winter s.:
Hours per week, examination: winter s.:3/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: cancelled
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Level:  
Guarantor: Sýkora David prof. Dr. RNDr.
Is interchangeable with: M402002
Examination dates   Schedule   
Annotation -
The goal of the presentations is to broaden and extend knowledge of the students in the area of separation techniques.
Last update: Sýkora David (18.09.2013)
Aim of the course -

Students will have extensive knowledge of the theory and practice of modern separation techniques.

Last update: VED402 (16.12.2013)
Literature -

A: Introduction to Mass Spectrometry - kniha, J.T. Watson and O.D. Sparkman, Wiley, 2007, ISBN: 978-0-470-51634-8.

A: Mass Spectrometry-A Textbook - kniha, J.H. Gross, 2004, Springer, ISBN: 3-540-40739-1.

A: Introduction to Modern Liquid Chromatography - kniha, L.R. Snyder, J.J. Kirkland and J.W. Dolan, Wiley, 2010, ISBN:978-0-470-16754-0.

A: Gas Chromatography and Mass Spectrometry-A Practical Guide - kniha, O.D. Sparkman, Z.E. Penton, and F.G. Kitson, 2011, Elsevier, ISBN:978-0-12-373628-4.

A: Practical HPLC Method Development - kniha, L.R. Snyder, J.J. Kirkland, J.L. Glajch; Wiley, 1997, ISBN:0-471-00703-X.

A: Chromatographic methods - kniha, A. Braithwaite, F.J. Smith; Blackie Academic & Proffessional, 1996, ISBN:0-7514-0158-7.

A: Gas Chromatography - kniha, I.A. Fowlis; ACOL, Wiley, 1995, ISBN:0-471-95467-5.

A: High Performance Liquid Chromatography - kniha, S. Lindsay; ACOL, Wiley, 1992, ISBN:0-471-93180-2.

A: Chromatography Today - kniha, C.F. Poole, S.K. Poole; Elsevier, 1991, ISBN:0-444-88492-0.

A: Chromatography (6th edition), Fundamentals and Applications of Chromatography and Related Differential Migration Methods, kniha, E. Heftmann, Part A, Elsevier, 2004, ISBN: 0-444-51107-5.

A: Modern Practice of Gas Chromatography - R.L. Grob, E.F. Barry, Wiley, 2004, ISBN: 978-0-471-22983-4.

A: HPLC for Pharmaceutical Scientists, Y.V. Kazakevich, R. LoBrutto, Wiley, 2007, ISBN: 978-0-471-68162-5.

A: Analytická separace látek - kniha, J. Churáček; SNTL, 1990.

A: High Performance Capillary Electrophoresis - firemní příručka, D.N. Heiger, Hewlett-Packard, 1992.

A: Basic Gas Chromatography - kniha, H.M. McNair and J.M. Miller, Wiley, 2009, ISBN: 978-0-470-43954-8.

A: Practical High-Performance Liquid Chromatography - kniha, V.R. Meyer, Wiley, 2010, ISBN: 978-0-470-68218-0.

A: The Troubleshooting and Maintenance Guide for Gas Chromatography - D. Rood, Wiley, 2007, ISBN: 978-0-527-31373-0.

Last update: VED402 (01.10.2013)
Syllabus -

1. Gas chromatograophy - detailed theory, van Deemter plots.

2. Gas chromatograophy - current trends.

3. High-performance chromatography - detailed theory, kinetic plots.

4. High-performance chromatography - current trends

5. Ultrahigh-performance chromatography.

6. Electrophoresis.

7. Capillary electrophoresis.

8. Separation on chips and high-throughput techniques.

9. Solid phase extraction - current status.

10. Simulated moving bead technology.

11. Supercritical fluid chromatography.

12. Mass spectrometry - 1.

13. Mass spectrometry - 2.

14. Webinars - useful source of information.

Last update: Sýkora David (26.09.2016)
Learning resources -

http://onlinelibrary.wiley.com/book/10.1002/9780470688427

Last update: Sýkora David (18.09.2013)
Entry requirements -

Students need to have basic knowledge of the separation methods.

Last update: Sýkora David (18.09.2013)
Registration requirements -

Students need to have basic knowledge of the separation methods.

Last update: Sýkora David (18.09.2013)
Teaching methods
Activity Credits Hours
Obhajoba individuálního projektu 0.5 14
Účast na přednáškách 1.5 42
Práce na individuálním projektu 1 28
Příprava na zkoušku a její absolvování 2 56
5 / 5 140 / 140
Coursework assessment
Form Significance
Regular attendance 10
Defense of an individual project 20
Oral examination 70

 
VŠCHT Praha