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The course is focused on the chemical sensors (mainly optical and electrochemical) which are designed and used primarily for the determination of drugs. The goal is to provide a comprehensive information about the basic principles and characteristics of sensors, their design, preparation, construction and application in various fields with emphasis on the pharmaceutical industry. New trends in the development of sensors are also monitored.
Last update: Broncová Gabriela (12.11.2012)
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Students will be able:
To describe the basic properties of chemical sensors. To understand the principles of chemical sensors. To design a simple sensor for the determination of pharmaceuticals and to evaluate its advantages and disadvantages for a given area of application.
Last update: VED402 (16.12.2013)
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R: Eggins B.R.: Chemical Sensors and Biosensors, Wiley, 2004. Available on-line at VSCHT R: Baldini F., Chester A.N., Homola J., Martelluci S.: Optical chemical sensors, Springer (2006): http://www.scribd.com/doc/38052553/Optical-Chemical-Sensors-by-Francesco-Baldini R: Wang J.: Analytical Electrochemistry, 3rd Ed, Wiley, 2006: R: http://onlinelibrary.wiley.com/book/10.1002/0471790303;jsessionid=6F5F957F1C2E7275987138AE0932256A.d01t04 R: http://www.vscht.cz/anl/paci/PAC/prezentace/senzory.pdf
A: Borisov, S. M.; Wolfbeis, O. S.: Optical Biosensors, Chemical Reviews (2008), 108, 423-461. Available on-line at VSCHT A: Comprehensive Analytical Chemistry: Electrochemical Sensor Analysis, ed. S. Alegret and A. Merkoci, Vol. 49 (2007), Elsevier. Available on-line at VSCHT A: Bakker E., Bühlmann P., Pretsch E.: Polymer Membrane Ion-Selective Electrodes�What are the Limits?; Electroanalysis 11 (1999) 915 -933. Available on-line at VSCHT A: Umasankar Yogeswaran and Shen-Ming Chen: A Review on the Electrochemical Sensors and Biosensors Composed of Nanowires as Sensing Material, Sensors 2008, 8(1), 290-313: http://www.mdpi.com/1424-8220/8/1/290 A: Biosensors and Chemical Sensors - Optimizing Performance Through Polymeric Materials, ed. Edelman P.G., Wang J., Vol 487 (1992), ACS. Available on-line at VSCHT A: Biosensor Design and Application, ed. Mathewson P.R., Finley J.W., Vol 511 (1992), ACS. Available on-line at VSCHT A: Chemical Sensors and Microinstrumentation, ed. Murray R.W., Dessy R.E., Heineman W.R., Janata J., Seitz W.R., Vol 403 (1989), ACS. Available on-line at VSCHT Last update: VED402 (01.10.2013)
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1. Sensors: general definition, classification and principle of operation, properties of requirement receptor as a sensor element 2. Optical sensors: introduction, properties, arrangements of components for the optical sensors 3. Optical sensors: evanescent sensors, special waveguide sensors 4. Optical sensors: interference sensors, reflective sensors, optical lattices 5. Optical sensors: Taper-miniaturized sensors, resonators, nanoparticles 6. Optical sensors: imaging sensors, sensor array, new sensor materials 7. Optical sensors: surface plasmon resonance (SPR) 8. Electrochemical sensors, ion-selective electrodes 9. Electrode arrays - electronic nose and tongue 10. Analytical applications of self-assemble layers 11. Enantiomeric recognition: complexation of receptor-analyte 12. Biosensors for fragments of nucleic acid fragments 13. Nanotechnology for the development of sensors 14. Sensor applications in pharmaceuticals and diagnostics Last update: Broncová Gabriela (13.11.2012)
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Sensors: http://www.mdpi.com/journal/sensors Elsevier: Sensors and Actuators B: http://www.journals.elsevier.com/sensors-and-actuators-b-chemical/ Elsevier: Biosensors and Bioelectronics: http://www.journals.elsevier.com/biosensors-and-bioelectronics/ Elsevier: Journal of Pharmaceutical and Biomedical analysis: http://www.journals.elsevier.com/journal-of-pharmaceutical-and-biomedical-analysis/ Last update: VED402 (03.10.2013)
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Physics, Analytical Chemistry Last update: VED402 (03.10.2013)
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Teaching methods | ||||
Activity | Credits | Hours | ||
Konzultace s vyučujícími | 0.1 | 3 | ||
Účast na přednáškách | 1 | 28 | ||
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi | 1 | 28 | ||
Příprava na zkoušku a její absolvování | 0.9 | 25 | ||
3 / 3 | 84 / 84 |
Coursework assessment | |
Form | Significance |
Examination test | 100 |