SubjectsSubjects(version: 953)
Course, academic year 2021/2022
  
Sensor analysis of pharmaceutically important compounds - N402066
Title: Senzorová analýza farmaceuticky významných látek
Guaranteed by: Department of Analytical Chemistry (402)
Faculty: Faculty of Chemical Engineering
Actual: from 2019
Semester: winter
Points: winter s.:3
E-Credits: winter s.:3
Examination process: winter s.:
Hours per week, examination: winter s.:2/0, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: cancelled
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Level:  
Guarantor: Šiškanova Taťjana doc. Mgr. CSc.
Is interchangeable with: M402044
Examination dates   Schedule   
Annotation -
The course is focused on the chemical sensors (mainly optical and electrochemical) which are designed and used primarily for the determination of drugs. The goal is to provide a comprehensive information about the basic principles and characteristics of sensors, their design, preparation, construction and application in various fields with emphasis on the pharmaceutical industry. New trends in the development of sensors are also monitored.
Last update: Broncová Gabriela (12.11.2012)
Aim of the course -

Students will be able:

To describe the basic properties of chemical sensors.

To understand the principles of chemical sensors.

To design a simple sensor for the determination of pharmaceuticals and to evaluate its advantages and disadvantages for a given area of application.

Last update: VED402 (16.12.2013)
Literature -

R: Eggins B.R.: Chemical Sensors and Biosensors, Wiley, 2004. Available on-line at VSCHT

R: Baldini F., Chester A.N., Homola J., Martelluci S.: Optical chemical sensors, Springer (2006): http://www.scribd.com/doc/38052553/Optical-Chemical-Sensors-by-Francesco-Baldini

R: Wang J.: Analytical Electrochemistry, 3rd Ed, Wiley, 2006:

R: http://onlinelibrary.wiley.com/book/10.1002/0471790303;jsessionid=6F5F957F1C2E7275987138AE0932256A.d01t04

R: http://www.vscht.cz/anl/paci/PAC/prezentace/senzory.pdf

A: Borisov, S. M.; Wolfbeis, O. S.: Optical Biosensors, Chemical Reviews (2008), 108, 423-461. Available on-line at VSCHT

A: Comprehensive Analytical Chemistry: Electrochemical Sensor Analysis, ed. S. Alegret and A. Merkoci, Vol. 49 (2007), Elsevier. Available on-line at VSCHT

A: Bakker E., Bühlmann P., Pretsch E.: Polymer Membrane Ion-Selective Electrodes�What are the Limits?; Electroanalysis 11 (1999) 915 -933. Available on-line at VSCHT

A: Umasankar Yogeswaran and Shen-Ming Chen: A Review on the Electrochemical Sensors and Biosensors Composed of Nanowires as Sensing Material, Sensors 2008, 8(1), 290-313: http://www.mdpi.com/1424-8220/8/1/290

A: Biosensors and Chemical Sensors - Optimizing Performance Through Polymeric Materials, ed. Edelman P.G., Wang J., Vol 487 (1992), ACS. Available on-line at VSCHT

A: Biosensor Design and Application, ed. Mathewson P.R., Finley J.W., Vol 511 (1992), ACS. Available on-line at VSCHT

A: Chemical Sensors and Microinstrumentation, ed. Murray R.W., Dessy R.E., Heineman W.R., Janata J., Seitz W.R., Vol 403 (1989), ACS. Available on-line at VSCHT

Last update: VED402 (01.10.2013)
Learning resources -

Sensors: http://www.mdpi.com/journal/sensors

Elsevier: Sensors and Actuators B: http://www.journals.elsevier.com/sensors-and-actuators-b-chemical/

Elsevier: Biosensors and Bioelectronics: http://www.journals.elsevier.com/biosensors-and-bioelectronics/

Elsevier: Journal of Pharmaceutical and Biomedical analysis: http://www.journals.elsevier.com/journal-of-pharmaceutical-and-biomedical-analysis/

Last update: VED402 (03.10.2013)
Syllabus -

1. Sensors: general definition, classification and principle of operation, properties of requirement receptor as a sensor element

2. Optical sensors: introduction, properties, arrangements of components for the optical sensors

3. Optical sensors: evanescent sensors, special waveguide sensors

4. Optical sensors: interference sensors, reflective sensors, optical lattices

5. Optical sensors: Taper-miniaturized sensors, resonators, nanoparticles

6. Optical sensors: imaging sensors, sensor array, new sensor materials

7. Optical sensors: surface plasmon resonance (SPR)

8. Electrochemical sensors, ion-selective electrodes

9. Electrode arrays - electronic nose and tongue

10. Analytical applications of self-assemble layers

11. Enantiomeric recognition: complexation of receptor-analyte

12. Biosensors for fragments of nucleic acid fragments

13. Nanotechnology for the development of sensors

14. Sensor applications in pharmaceuticals and diagnostics

Last update: Broncová Gabriela (13.11.2012)
Registration requirements -

Physics, Analytical Chemistry

Last update: VED402 (03.10.2013)
Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0.1 3
Účast na přednáškách 1 28
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 0.9 25
3 / 3 84 / 84
Coursework assessment
Form Significance
Examination test 100

 
VŠCHT Praha