SubjectsSubjects(version: 954)
Course, academic year 2019/2020
Environmental Toxicology and Ecotoxicology - P240001
Title: Environmentální toxikologie a ekotoxikologie
Guaranteed by: Department of Environmental Chemistry (240)
Faculty: Faculty of Environmental Technology
Actual: from 2019 to 2022
Semester: both
Points: 0
E-Credits: 0
Examination process:
Hours per week, examination: 3/0, other [HT]
Capacity: winter:unknown / unknown (unknown)
summer:unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Note: course is intended for doctoral students only
can be fulfilled in the future
you can enroll for the course in winter and in summer semester
Guarantor: Kočí Vladimír prof. Ing. Ph.D., MBA
Is interchangeable with: AP240001
Examination dates   Schedule   
Annotation -
The main goal of this course is to explain the principles of toxicity testing for industrial purposes like hazardous waste characterisation. The student will be guided through the whole process of toxicity testing from sample collection, planning of experimental design to final data interpretation. Broad spectrum of toxicity tests is demonstrated.
Last update: Pátková Vlasta (15.05.2018)
Aim of the course -

Student will be able to interpret dose-response curve and other toxicity indexes like EC50, NOEC, LOEC etc. Students get knowledge of broad variety of toxicity tests at different trophic levels and biological organisation.

Last update: Pátková Vlasta (15.05.2018)
Literature -

R: Michael C. Newman: Fundamentals of Ecotoxicology, Ann Arbor Press, Chelsea

R: Wayne G. Landis: Introduction to Environmental Toxicology, Lewis Publishers, CRC Press Company.

A: Kočí, V., Mocová, K.A.: Ekotoxikologie pro chemiky (skripta). VŠCHT Praha 2009, pp200.

A: Ekotoxikologické biotesty. Editor CD: Vladimír Kočí, Blahoslav Maršálek, Olga Halousková. ©Vodní zdroje EKOMONITOR spol. s r.o., 2005.

Last update: Sýkora Vladimír (13.01.2021)
Learning resources -


websites of department 240

Last update: Pátková Vlasta (15.05.2018)
Syllabus -

1.Relationship between chemical analysis and bioassays in an environmental monitoring. Ecotoxicology nad legislation.

2.Toxicity. Design of toxicity testing. Bioconcentration. Bioaccumulation. Biomagnification. Fundamental ecotoxicological indexes and parameters. Dose-response relationship.

3.Determination of toxicity in laboratory. Bioassays.

4.Toxicity testing procedure. Environmental samples. Chemicals testing. Sampling. Pretreatment of samples. Range-finding test. Basic test.

5.Statistical evaluation of toxicity testing. Interpretation of dose-response relationship. Ecotoxicological indexes. Calculations. Multivariate ordination techniques.

6.Biochemical level of toxicity. Molecular effects. Endocrine disruption.

7.Cells, tissues and organs effects. Sublethal effects to Individuals. Acute and Chronic Lethal Effects to Individuals. Effects on Populations, Communities and Ecosystems.

8.Mutagenity testing. Mutagenesis. Teratogenity testing. Endocrine disruptors.

9.Toxicity testing on plants. Aquatic and terrestrial plants. Description of methods. Phytoremediation.

10.Toxicity testing on protozoa. Algal toxicity testing.

11.Toxicity testing on consuments. Crustaceans and zooplancton. Fish testing. Terrestrial toxicity testing. Determination of toxicity of sediments. Toxicity testing on terrestrial consuments. Worms, springtails. Heterogeneity of soil.

12.Toxicity testing on destruents. Bacterial bioassays. Soil enzymatic activity.

13.Biomarkers of exposition. Biomakers of effect. Bioindicators.

14.Mesocosm, microcosms and in-situ toxicity testing.

Last update: Pátková Vlasta (15.05.2018)
Course completion requirements -

Project presentation and final exam.

Last update: Březina Milan (17.11.2018)
Coursework assessment
Form Significance
Oral examination 100