SubjectsSubjects(version: 954)
Course, academic year 2019/2020
  
Transition Metals in Organic Synthesis - S110014
Title: Transition Metals in Organic Synthesis
Guaranteed by: Department of Organic Chemistry (110)
Faculty: Faculty of Chemical Technology
Actual: from 2011 to 2020
Semester: winter
Points: winter s.:6
E-Credits: winter s.:6
Examination process: winter s.:
Hours per week, examination: winter s.:3/1, Ex [HT]
Capacity: unknown / unknown (unknown)
Min. number of students: unlimited
State of the course: taught
Language: English
Teaching methods: full-time
Teaching methods: full-time
Level:  
Guarantor: Dvořák Dalimil prof. Ing. CSc.
Examination dates   Schedule   
Syllabus - Czech

1. Formalism (oxidation state, d-electron configuration, 18-electron rule).

2. Basic types of ligands (s-complexes).

3. Basic types of ligands (p-complexes).

4. Reactions in coordination sphere of transition metals (ligand substitution, oxidative addition, reductive elimination, insertion, transmetallation).

5. Nucleophilic attack on ligands coordinated to transition metals.

6. Electrophilic attack on ligands coordinated to transition metals.

7. Homogeneous catalytic reactions (hydrogenation, hydrosilation, hydrocyanation, alkene and alkyne polymerisation, carbonylation reactions).

8. Synthetic applications of transition metal hydrides, organocuprates.

9. Synthetic applications of complexes from insertion of alkenes and alkynes.

10. Synthetic applications of complexes from oxidative addition followed with insertion of alkene, alkyne and carbon monoxide (cross coupling, Heck reaction).

11. Synthetic applications of transition metal carbonyl complexes.

12. Synthetic applications of transition metal carbene complexes (reactions of nucleophilic and electrophilic carbenes, alkene metathesis, metal-catalysed decomposition of diazo compounds).

13. Synthetic applications of h3-allyl transition metal complexes.

14. Synthetic applications of transition metal h6-arene complexes (Cr(CO)3 and FeCp+ complexes).

Last update: KNOBLOCL (13.03.2012)
 
VŠCHT Praha