Subjects

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Bioorganic Chemistry of Natural Compounds - N342001

Title:	Bioorganická chemie přírodních látek
Guaranteed by:	Department of Chemistry of Natural Compounds (342)
Faculty:	Faculty of Food and Biochemical Technology
Actual:	from 2013 to 2013
Semester:	winter
Points:	winter s.:5
E-Credits:	winter s.:5
Examination process:	winter s.:
Hours per week, examination:	winter s.:2/1, C+Ex [HT]
Capacity:	200 / unlimited (unknown)
Min. number of students:	unlimited
State of the course:	taught
Language:	Czech
Teaching methods:	full-time
Teaching methods:	full-time
Level:
Note:	course can be enrolled in outside the study plan enabled for web enrollment

Guarantor:	Staněk Jan doc. RNDr. CSc. Raich Ivan doc. Dr. Ing.
Is interchangeable with:	N342501

Examination dates Schedule

Annotation -

The course covers basic groups of natural compounds, their properties and utilization. It explains also basic concepts related to structure of molecules, their stereochemistry and chirality including structure-biological activity relationships.

Last update: TAJ342 (18.12.2013)

Aim of the course -

Students will be able to:

Name compounds according to nomenclature of organic compounds

Describe structure, properties and reactions of individual groups of organic compounds as well as their biogenesis

Assess configuration, chirality and likely conformations based on the structural formula

Depict reaction mechanisms of basic reaction types

Last update: TAJ342 (30.09.2013)

Literature -

R: McMurry J.: Organic chemistry, 8th Ed., Brooks/Cole, Cengage Learning, 2012, 9780840054449

Last update: TAJ342 (27.09.2013)

Syllabus -

1. Bioorganic chemistry, definition of natural compounds, overview, occurrence, and nomenclature

2. Stereochemistry of natural compounds, chirality

3. Isolation of a compound, structure determination

4. Relationships between structure, biogenesis and biological activity

5. Monosaccharides, nucleophillic addition on carbonyl group

6. Oligosaccharides, polysaccharides

7. Amines, basicity, nucleophilicity

8. Alkaloids, nucleosides, narcotics, drugs

9. Hydroxy acids, acidity

10. Amino acids, peptides, proteins

11. Lipids, prostaglandins

12. Terpenoids, electrophilic addition, polyphenols

13. Antibiotics, narcotics, drugs, patent policy

14. Metabolic pathways assessment, precursor labeling, metabolites tracing, falsification of foodstuffs

Last update: TAJ342 (27.09.2013)

Learning resources -

Lecture notes

Last update: TAJ342 (27.09.2013)

Registration requirements -

Organic chemistry I

Last update: TAJ342 (27.09.2013)

Teaching methods
	Activity	Credits	Hours
	Konzultace s vyučujícími	0.5	14
	Účast na přednáškách	1	28
	Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi	1	28
	Příprava na zkoušku a její absolvování	2	56
	Účast na seminářích	0.5	14
		5 / 5	140 / 140

Coursework assessment
Form	Significance
Regular attendance	20
Continuous assessment of study performance and course -credit tests	20
Oral examination	60