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This course introduces students to the forensic DNA analysis as the dominant method of determining the origin of biological material. It describes biological principles on which the field is based, application circuits (criminology, kinship analysis, identification analysis, bioarcheology, recreational genetics), principles of analysis from the collection of biological material to final evaluation. It brings an overview of non-ID analysis and includes the basics of forensic statistics in the field of genetic analysis.
Last update: Kubová Petra (19.12.2017)
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Students will be able to: communicate effectively in the field of forensic DNA analysis (verbal interpretation of data, formulation of conclusions of expert reports, expert arguments in court). In addition they will be able to understand the basics of DNA analysis and its integration with the other forensic sciences and basic and additional applications and capabilities field; shall know the current commonly used methods and expertise understanding their nature, they will be able to claim the standard expertise to design satisfactory method of analysis, will be able to understand the issue of quality in the laboratory and will have an idea about the basic legal aspects of the field. Last update: Kubová Petra (19.12.2017)
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R:John M. Butler;Fundamentals of Forensic DNA Typing;Academic Press, 2009;9780123749994 R:John M. Butler;Advanced Topics in Forensic DNA Typing: Methodology;Academic Press, 2011;9780123745132 A:John M. Butler;Forensic DNA Typing, Second Edition: Biology, Technology, and Genetics of STR Markers;Academic Press, 2005;9780121479527 A:Richard Li;Forensic Biology: Identification and DNA Analysis of Biological Evidence;CRC Press 2008;9781420043433 A:Ron C. Michaelis et al.;A Litigator's Guide to DNA:From the Laboratory to the Courtroom;Academic Press, 2008;9780123740366 A:N. Rudin, K. Inman;An Introduction to Forensic DNA Analysis, Second Edition;CRC Press 2001;9780849302336 Last update: Kubová Petra (19.12.2017)
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1. Introduction to forensic genetics, forensic genetics history, relationship to forensic biology and serology 2.Collection of biological traces and extraction of DNA from forensic samples 3.charakterization of DNA - DNA quantification, determination of quality and species specificity 4.Individuality as a complex concept, the principles of personal identification 5.Repetitive sequences of the human genome, STR markers 6.Methods of analysis on STR markers, the genetic profile analysis of composite samples 7.Forensic analysis of gonozomal markers and mitochondrial DNA 8.Population forensic genetics, forensic statistics 9.Non-human typing - forensic analysis of fauna and flora, forensic microbiology 10.Prediction of phenotype via DNA analysis and "non-ID" forensic DNA analysis 11.Forensic genetics laboratory, DNA databasing 12.Genogeography, genogenealogy, paleogenetics and biomolecular archaeology 13.Quality in the laboratory 14.Genetics as part of the forensic and investigative sciences and the Czech legal system Last update: Kubová Petra (19.12.2017)
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none Last update: Kubová Petra (19.12.2017)
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Molecular genetics, DNA analysis Last update: Kubová Petra (19.12.2017)
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| Teaching methods | ||||
| Activity | Credits | Hours | ||
| Účast na přednáškách | 1 | 28 | ||
| Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi | 2 | 56 | ||
| Příprava na zkoušku a její absolvování | 2 | 56 | ||
| 5 / 5 | 140 / 140 | |||