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Engineering of Chemical and Pharmaceutical Processes course is aimed at providing the understanding of the unit operations employed in the pharmaceutical industry, in the chemical part of API synthesis, as well as in the dosage form manufacturing. Operations or their aspects that are beyond the scope of general chemical engineering courses constitute the essential part of this course. The understanding of the unit operations and process principles is supported by substantial amount of insight into properties of particulate solids, considering their key role in contemporary solid dosage forms design and manufacturing, and also by introductory course into the process control and safety. Last update: Zámostný Petr (19.02.2018)
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R:Rhodes M.,Introduction to Particle Technology,Wiley,New York,2008,0471984833 R:Hickey A.J.,Pharmaceutical Process Engineering,M.Dekker,2001,0824702980 A:Levin M.,Pharmaceutical process scale up,M.Dekker,2002,0824706250 A:Klefenz H.,Industrial Pharmaceutical Biotechnology,Wiley,N.Y.,2002,3527299955 A:Fogler H.S.,Elements of Reaction Engineering,Prentice,Hall,New Jersey,2000,0130473944 Last update: Zámostný Petr (19.02.2018)
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https://e-learning.vscht.cz/course/view.php?id=408 Last update: Zámostný Petr (19.02.2018)
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1. Characteristics and characterization of particles and particulate systems 2. Introduction to mechanics of particulate solids 3. Transport, storage, and dosing of particulate solids 4. Particle size reduction and classification 5. Particle agglomeration processes, high-shear, and fluidized-bed granulation 6. Agglomeration processes scale up, general scale up considerations 7. Compaction, extrusion, spheronization 8. Tablet compression 9. Mixing and segregation in particulate systems 10. Processes involving particulate solid interaction with liquids 11. Applied reaction kinetics 12. Reaction kinetics of biotechnological processes 13. Chemical reactors for small-scale operations and bioreactors 14. Introduction to process control, safety considerations in chemical and pharmaceutical processes
Last update: Zámostný Petr (19.02.2018)
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The evaluation is based on the results of a written examination from lectures, solution of homework, as well as activity during lectures and exercises. Last update: Zámostný Petr (19.02.2018)
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| Teaching methods | ||||
| Activity | Credits | Hours | ||
| Konzultace s vyučujícími | 0.5 | 14 | ||
| Účast na přednáškách | 1.5 | 42 | ||
| Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi | 1 | 28 | ||
| Příprava na zkoušku a její absolvování | 2 | 56 | ||
| 5 / 5 | 140 / 140 | |||
| Coursework assessment | |
| Form | Significance |
| Examination test | 70 |
| Continuous assessment of study performance and course -credit tests | 30 |