SubjectsSubjects(version: 948)
Course, academic year 2023/2024
  
Biotechnology in Chemical and Pharmaceutical Industry - M319017
Title: Biotechnologie v chemické a farmaceutické výrobě
Guaranteed by: Department of Biotechnology (319)
Faculty: Faculty of Food and Biochemical Technology
Actual: from 2020
Semester: winter
Points: winter s.:5
E-Credits: winter s.:5
Examination process: winter s.:
Hours per week, examination: winter s.:2/2, C+Ex [HT]
Capacity: unlimited / unlimited (unknown)
Min. number of students: unlimited
Language: Czech
Teaching methods: full-time
Teaching methods: full-time
Level:  
For type: Master's (post-Bachelor)
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Masák Jan prof. Ing. CSc.
Interchangeability : N319035
This subject contains the following additional online materials
Annotation -
Last update: Masák Jan prof. Ing. CSc. (03.02.2018)
Chemical and pharmaceutical industry extends the use of biotechnological processes for obtaining new compounds or for reducing costs and environmental impact of the production of current compounds. Introductory lectures will provide detailed information about the current range of implementation of biotechnological processes in these industries. Attention is also given to explain the procedures for development of industrial strains achieving the high production of required compounds and then the specific features of the unit operations up-stream and down-stream processes for different types of biotechnology are discussed. The various types of processes are then discussed using examples of production of particular substances applied in the chemical and pharmaceutical industries. Special attention is paid to biotransformation processes. In the seminar, students work out individual theme the output of which is the design of a biotechnological process for the production of a selected substance.
Aim of the course -
Last update: Hladíková Jana (20.12.2017)

Students will be able to:

select appropriate procedures for the preparation of industrial biological agents (microorganisms, enzymes, plant or animal tissue culture);

generally suggest biotechnological process for the production a substance;

evaluate the process, health and economic risks of a particular biotechnology;

apply extensive knowledge in the design of biotechnological processes in the chemical and biotechnology industries

Literature -
Last update: Hladíková Jana (20.12.2017)

R:Moo-Young, M:Comprehensive Biotechnology (2nd ed.), Elsevier, Amsterdam, 2011,9780080885049

A:Rehm,H.-J.,Reed G.: Biotechnology, 12 Vols., 2nd Ed, Wiley, Weinheim, 2008,9783527620821

A:Flickinger, M.C.: Encyclopedia of Bioprocess Technology, Wiley, 2008,9780471250586

A:Ho, R.J.Y: Biotechnology and Biopharmaceuticals, Wiley, 2003,0471206903

Learning resources -
Last update: Masák Jan prof. Ing. CSc. (03.02.2018)

https://e-learning.vscht.cz/

Requirements to the exam -
Last update: Masák Jan prof. Ing. CSc. (03.02.2018)

Preparation and defense of the seminar paper.

Syllabus -
Last update: Hladíková Jana (20.12.2017)

1. Introduction - the status of biotechnology in the chemical and pharmaceutical industry

2. Characteristics of biotechnological processes

3. The development of industrial strains - physiological adaptation, gene modification, transformation of higher organisms

4. Biotechnological production of primary and secondary metabolites - unit operations, process management, economic balance

5. Biotechnological production of biopharmaceuticals - characteristics of the processes

6. Biotransformation - basic characteristics of the processes

7. Biotransformation - examples

8. Antibiotics - characteristics, production organisms, technological processes

9. Antibiotics - the current state of world production, research and development

10. Cancerostatics - characteristics, production organisms, technological processes

11. Alkaloids - characteristics, production organisms, technological processes

12. Vitamins - characteristics, production organisms, technological processes

13. Enzymes - characteristics, production organisms, technological processes

14. Polysaccharides - characteristics, production organisms, technological processes

Registration requirements -
Last update: Hladíková Jana (20.12.2017)

Biochemistry, Microbiology, Bioengineering

Course completion requirements -
Last update: Masák Jan prof. Ing. CSc. (03.02.2018)

Course credit based on the presentation of the seminar paper.

Oral exam.

Teaching methods
Activity Credits Hours
Účast na přednáškách 2 56
Práce na individuálním projektu 1 28
Příprava na zkoušku a její absolvování 2 56
5 / 5 140 / 140
 
VŠCHT Praha