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Last update: SMIDOVAL (18.05.2011)
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Last update: SMIDOVAL (18.05.2011)
J. Xiong, Essential Bioinformatics, Cambridge University Press 2006, ISBN 0521600820 J.-M. Claverie, C. Notredame, Bioinformatics For Dummies, For Dummies 2006, ISBN 0470089857 M. Zvelebil, J. Baum, Understanding Bioinformatics, Garland Science 2007, ISBN 0815340249 |
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Last update: SMIDOVAL (18.05.2011)
K zápočtu a ke zkoušce bude požadováno:
1. Test v polovině semestru
2. Písemná zkouška |
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Last update: SMIDOVAL (18.05.2011)
1) Background basics I - Structure of DNA and RNA. The central dogma. Gene structure and control. 2) Background basics II - Evolution. Protein structure and its implication for bioinformatics. Dealing with databases. 3) Sequence alignment I - Pairwise sequence alignment. Similarity database searching. 4) Sequence alignment II - Multiple sequence alignment. Profiles and Hidden Markov Models. 5) Genome characteristics - Gene Detection and Genome Annotation. Promoter and regulatory element prediction. 6) Evolutionary processes - Recovering evolutionary history. Building phylogenetic trees. 7) Structural bioinformatics I - Protein structure basics. Nucleic acid structure basics. 8) Structural bioinformatics II - Prediction of protein structure 9) Structural bioinformatics III - Prediction of nucleic acids structure (RNA) 10) Proteome and gene expression analysis 11) High throughput screening experiments and their analysis 12) Data mining in bioinformatics 13) Biomedical text mining |