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Last update: Cibulka Radek prof. Ing. Ph.D. (06.07.2022)
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Last update: Cibulka Radek prof. Ing. Ph.D. (06.07.2022)
Students will be able to: understand approaches to suggest suitable target understand principles of basic computational approaches for drug design understand approaches to develop leading structure know modern approaches for drug discovery.
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Last update: Cibulka Radek prof. Ing. Ph.D. (06.07.2022)
R:K. Stromgaard, P. Krogsgaard-Larsen, U. Madsen (Eds.): Textbook of Drug Design and Discovery, CRC Press, 5th Edition 2016; ISBN 9781032339948 R:R. B. Silverman, M. W. Holladay: The Organic Chemistry of Drug Design and Drug Action, Academic Press 2014; ISBN 978-0-12-382030-3 A: C. Rostron: Drug Design and Development, Oxford 2020; ISBN: 9780198749318 |
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Last update: Fialová Jana (05.05.2022)
http://en.wikipedia.org/wiki/Organocatalysis |
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Last update: Cibulka Radek prof. Ing. Ph.D. (06.07.2022)
1. The Drug Design and Discovery process 2. Selecting the right target 3. How drugs work 4. Computer-aided drug design I: Structure-Based Drug Design 5. Computer-aided drug design I: Ligand-Based Drug Design 6. Natural compounds in Drug Discovery 7. Fragment-Based Drug Design 8. Hit discovery and lead optimisation I: Structure-Activity Relationships 9. Hit discovery and lead optimisation II: Hit-to-Lead 10. Hit discovery and lead optimisation III: Lead Optimisation 11. Prodrugs 12. Recent advances in Drug Design and Medicinal Chemistry 13. Drugs and their therapeutic landscape 14. Decision making in Drug Discovery |
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Last update: Fialová Jana (05.05.2022)
It is compulsory to pass written examination test. |