SubjectsSubjects(version: 877)
Course, academic year 2020/2021
  
Engineering in Chemical and Pharmaceutical Processes - AM111014
Title: Engineering in Chemical and Pharmaceutical Processes
Guaranteed by: Department of Organic Technology (111)
Actual: from 2019
Semester: winter
Points: winter s.:5
E-Credits: winter s.:5
Examination process: winter s.:
Hours per week, examination: winter s.:3/0 C+Ex [hours/week]
Capacity: 20 / unknown (unknown)
Min. number of students: unlimited
Language: English
Teaching methods: full-time
Level:  
For type: Master's (post-Bachelor)
Additional information: http://tresen.vscht.cz/kot/english/tag/pharmaceutical-engineering/
Note: course can be enrolled in outside the study plan
enabled for web enrollment
Guarantor: Zámostný Petr prof. Ing. Ph.D.
This subject contains the following additional online materials
Annotation
Last update: Zámostný Petr prof. Ing. Ph.D. (19.02.2018)
Engineering of Chemical and Pharmaceutical Processes course is aimed at providing the understanding of the unit operations employed in the pharmaceutical industry, in the chemical part of API synthesis, as well as in the dosage form manufacturing. Operations or their aspects that are beyond the scope of general chemical engineering courses constitute the essential part of this course. The understanding of the unit operations and process principles is supported by substantial amount of insight into properties of particulate solids, considering their key role in contemporary solid dosage forms design and manufacturing, and also by introductory course into the process control and safety.
Literature
Last update: Zámostný Petr prof. Ing. Ph.D. (19.02.2018)

R:Rhodes M.,Introduction to Particle Technology,Wiley,New York,2008,0471984833

R:Hickey A.J.,Pharmaceutical Process Engineering,M.Dekker,2001,0824702980

A:Levin M.,Pharmaceutical process scale up,M.Dekker,2002,0824706250

A:Klefenz H.,Industrial Pharmaceutical Biotechnology,Wiley,N.Y.,2002,3527299955

A:Fogler H.S.,Elements of Reaction Engineering,Prentice,Hall,New Jersey,2000,0130473944

Learning resources
Last update: Zámostný Petr prof. Ing. Ph.D. (19.02.2018)

https://e-learning.vscht.cz/course/view.php?id=408

Syllabus
Last update: Zámostný Petr prof. Ing. Ph.D. (19.02.2018)

1. Characteristics and characterization of particles and particulate systems

2. Introduction to mechanics of particulate solids

3. Transport, storage, and dosing of particulate solids

4. Particle size reduction and classification

5. Particle agglomeration processes, high-shear, and fluidized-bed granulation

6. Agglomeration processes scale up, general scale up considerations

7. Compaction, extrusion, spheronization

8. Tablet compression

9. Mixing and segregation in particulate systems

10. Processes involving particulate solid interaction with liquids

11. Applied reaction kinetics

12. Reaction kinetics of biotechnological processes

13. Chemical reactors for small-scale operations and bioreactors

14. Introduction to process control, safety considerations in chemical and pharmaceutical processes

Course completion requirements
Last update: Zámostný Petr prof. Ing. Ph.D. (19.02.2018)

The evaluation is based on the results of a written examination from lectures, solution of homework, as well as activity during lectures and exercises.

Teaching methods
Activity Credits Hours
Konzultace s vyučujícími 0,5 14
Účast na přednáškách 1,5 42
Příprava na přednášky, semináře, laboratoře, exkurzi nebo praxi 1 28
Příprava na zkoušku a její absolvování 2 56
5 / 5 140 / 140
 
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